Gene Mb2448c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2448c
Gene length294 bp
IdentifierMb2448c
Location 2689667 bp
Protein summary information
Molecular mass11065.7 Da
Isoelectric point11.8577
Protein length97 amino acids
Orthologs
M. tuberculosis H37RvRv2424c
Cross-references
InterProIPR002525
UniProtKB/TrEMBLQ7TYL7
SWISS-MODELA0A1R3Y137
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSPOSASE [FIRST PART]
CommentsMb2448c, -, len: 97 aa. Similar to 5' end of Rv2424c, len: 333 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 67 aa overlap). Probable transposase for IS1558, similar to IS element proteins e.g. AL021957|Rv2177c|MTV021_10 from Mycobacterium tuberculosis (221 aa), FASTA scores: opt: 1491, E(): 6.2e-87, (98.6% identity in 221 aa overlap); P19780|YIS1_STRCO HYPOTHETICAL INSERTION ELEMENT IS110 from Streptomyces coelicolor (45 aa), FASTA scores: opt: 203, E(): 1.7e-05; (27.3% identity in 238 aa overlap); etc. Contains PS01159 WW/rsp5/WWP domain signature. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv2424c exists as a single gene. In Mycobacterium bovis, a frameshift due to a 2 bp deletion (gt-*) splits Rv2424c into 2 parts, Mb2447c and Mb2448c.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS26896672689960-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2448c|Mb2448c
MQCRAREERPGRKTDLLDAEWLVHLLECGLLRGWLIPPADIKAARDVIRYRRKLVEHRTSKLQRLGNASRRRDQGRQRGVLGHPQVGAGDGGGAHRR
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