Gene Mb2491c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE DNA GLYCOSYLASE |
| Comments | Mb2491c, -, len: 268 aa. Equivalent to Rv2464c,len: 268 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 268 aa overlap). Possible DNA glycosylase (EC 3.2.2.-), showing some similarity to several other DNA glycosylases e.g. Q9F308|SCC80.11c PUTATIVE DNA REPAIR HYDROLASE (FRAGMENT) from Streptomyces coelicolor (306 aa), FASTA scores: opt: 894, E(): 6.1e-51,(51.05% identity in 282 aa overlap); O50606|MUTM|FPG_THETH FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE (EC 3.2.2.23) from Thermus aquaticus (267 aa), FASTA scores: opt: 342, E(): 4.6e-15, (32.4% identity in 250 aa overlap); Q9RCW5|SCM10.34c PUTATIVE FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE from Streptomyces coelicolor (287 aa), FASTA scores: opt: 321, E(): 1.1e-13, (29.35% identity in 259 aa overlap); etc. Identical to AAK46839|MT2539 FORMAMIDOPYRIMIDINE-DNA GLYCOSYLASE from Mycobacterium tuberculosis strain CDC1551. Also similar to other M. tuberculosis DNA glycosylases e.g. MTCY71.37 (32.9% identity in 277 aa overlap). BELONGS TO THE FPG FAMILY. |
| Functional category | Information pathways |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2735022 | 2735828 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2491c|Mb2491c
MPEGHTLHRLARLHQRRFAGAPVSVSSPQGRFADSASALNGRVLRRASAWGKHLFHHYVGGPVVHVHLGLYGTFTEWARPTDGWLPEPAGQVRMRMVGAEFGTDLRGPTVCESIDDGEVADVVARLGPDPLRSDANPSSAWSRITKSRRPIGALLMDQTVIAGVGNVYRNELLFRHRIDPQRPGRGIGEPEFDAAWNDLVSLMKVGLRRGKIIVVRPEHDHGLPSYLPDRPRTYVYRRAGEPCRVCGGVIRTALLEGRNVFWCPVCQT
Bibliography
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