Gene Mb2536c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2536c
Gene length1338 bp
IdentifierMb2536c
Location 2790053 bp
Protein summary information
Molecular mass46074.1 Da
Isoelectric point10.406
Protein length445 amino acids
Orthologues
M. tuberculosisRv2508c
Cross-references
InterProIPR016196, IPR024671
UniProtKB/TrEMBLQ7TYF2
SWISS-MODELA0A1R3Y1F8
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED INTEGRAL MEMBRANE LEUCINE AND ALANINE RICH PROTEIN
CommentsMb2536c, -, len: 445 aa. Equivalent to Rv2508c,len: 445 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 445 aa overlap). Probable conserved integral membrane leu-, ala-rich protein, equivalent to Q9CCU4|ML0430 PUTATIVE MEMBRANE PROTEIN from Mycobacterium leprae (454 aa) (alias O07710|MLCL383.37 longer 10 aa),FASTA scores: opt: 2205, E(): 2.5e-124, (75.75% identity in 441 aa overlap). Also similar to hypothetical or membrane proteins e.g. BAB50841|MLL4103 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (458 aa),FASTA scores: opt: 396, E(): 2.4e-16, (27.75% identity in 447 aa overlap); Q9RKX9|SC6D7.19c PUTATIVE INTEGRAL MEMBRANE PROTEIN from Streptomyces coelicolor (486 aa),FASTA scores: opt: 323, E(): 5.7e-12, (28.95% identity in 428 aa overlap); P42306|YXIO_BACSU PROBABLE INTEGRAL MEMBRANE PROTEIN from Bacillus subtilis (428 aa), FASTA scores: opt: 220, E(): 7.2e-06, (20.35% identity in 413 aa overlap); etc. Also similar to proteins from Mycobacterium tuberculosis e.g. Q10564|Y876_MYCTU|Rv0876c|MT0899|MTCY31.04c (548 aa),FASTA scores: opt: 184, E(): 0.0012, (24.7% identity in 466 aa overlap).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS27900532791390-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2536c|Mb2536c
MNNPGSRAGTLLHFRVVAWAMWDCGSTGLNAIVTTFVFSVYLTSAVGQGLPGGTSPASWLGRAGAVAGLTIGVLAPVVGVWVESPHRRRVALSVLTGTAVALTCAMFLIRDDPRYLWAGLVLLAATAASSDLSSVPYNAMLRQLSTPSTAGRISGFGWASGYVGSVALLLVIYLGFMSGSGSQRGLLQLPVANGLNVRMAMLVAAAWLALLGLPLLLVAHRLPDSGAASHPSTGLLGGYRKLWTEISAEWRRDRNLVYFLVASAIFRDGLAAIFAFGAVLGVNAYGLTQADVLIFGAAASVVAAVGAVLGGFVDHRIGSKPVIVGSLAAIIAAALTLLTLSGPTAFWACGLLLCVFIGPAQSSARALLLHMAQHGKEGVAFGLYTMTGRAVSFLGPWLFSVFVDVFHTVRAGLGGVCLVLTTGLLLMLRVQVSRHGGALTTAQSS
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