Gene Mb2551c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2551c
Gene length1413 bp
IdentifierMb2551c
Location 2804926 bp
Protein summary information
Molecular mass49325.5 Da
Isoelectric point5.3016
Protein length470 amino acids
Orthologs
M. tuberculosis H37RvRv2522c
M. tuberculosis MTBC0mtbc0_002686
Cross-references
InterProIPR002933, IPR011650
UniProtKB/TrEMBLQ7TYD9
SWISS-MODELA0A1R3Y1P4
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb2551c, -, len: 470 aa. Equivalent to Rv2522c,len: 470 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 470 aa overlap). Conserved hypothetical protein, equivalent, but longer 20 aa, to Q9X7E4|ML1193|MLCB458.08 from HYPOTHETICAL 46.6 KDA PROTEIN Mycobacterium leprae (442 aa), FASTA scores: opt: 2521, E(): 4.1e-142, (86.35% identity in 440 aa overlap). Also similar to various proteins e.g. Q9K425|SCG22.20 PUTATIVE PEPTIDASE from Streptomyces coelicolor (451 aa),FASTA scores: opt: 1097, E(): 1.1e-57, (42.5% identity in 451 aa overlap); Q9FCK3|2SC3B6.09 PUTATIVE PEPTIDASE from Streptomyces coelicolor (470 aa), FASTA scores: opt: 669,E(): 2.8e-32, (34.2% identity in 462 aa overlap); Q98AF9|MLL6018 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (486 aa), FASTA scores: opt: 622,E(): 1.7e-29, (33.95% identity in 442 aa overlap); Q9RSU7|DR2025 ARGE/DAPE/ACY1 FAMILY PROTEIN from Deinococcus radiodurans (459 aa), FASTA scores: opt: 616,E(): 3.7e-29, (34.15% identity in 442 aa overlap); etc (include some similarity to hypothetical proteins from C. elegans and yeast). Alternative start possible at 6687 but then no RBS obvious.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28049262806338-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2551c|Mb2551c
MSASRRRIASKSGFSCDSASARELVERVREVLPSVRCDLEELVRIESVWADPDRRDEVHRSARAVADLLSQAGFDDVRIVSERGAPAVIARYPAPPGAPTVLLYAHHDVQPEGDRGQWVSPPFEPTERGGRLYGRGTADDKAGIATHVAAFWAHGGRPPVGVTVFVEGEEESGSPSLGRLLAAHRDALAADVIVIADSDNWSTDIPALTVSLRGMADCVVEVATLDHGLHSGLWGGVVPDALTVLVRLLASLHDDDGNVAVAGMHESTAARVDYPAGRVRAESGLLDGVSEIGTGSVPQRLWAKPAITVIGIDTTSVAAASNTLIPRARAKISIRVAPGGDATAHLDAVEAHLRRHAPWGAQVTVTRGEVGQPYAIEASGPVYDAARSAFRQAWGADPIDMGMGGSIPFIAEFAAAFPQATILVTGVEDPGTQAHSVNESLHLGVLERAATAEALLLAKLAAIPTGRAEA
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