Gene Mb2562c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namenusB
Gene length471 bp
IdentifierMb2562c
Location 2825051 bp
Protein summary information
Molecular mass16784.2 Da
Isoelectric point6.8063
Protein length156 amino acids
Cross-references
UniProtKB/TrEMBLX2BL35, Q7TYC8
SWISS-MODELQ7TYC8
General annotation
TypeCDS
FunctionUnknown
ProductN UTILIZATION SUBSTANCE PROTEIN NUSB (NUSB PROTEIN)
CommentsMb2562c, nusB, len: 156 aa. Equivalent to Rv2533c,len: 156 aa, from Mycobacterium tuberculosis strain H37Rv,(99.4% identity in 156 aa overlap). nusB, N utilization substance protein (see citation below), equivalent to Q9CCR9|NUSB_MYCLE|ML0523 N UTILIZATION SUBSTANCE PROTEIN B from Mycobacterium leprae (190 aa), FASTA scores: opt: 749, E(): 2.6e-41, (75.7% identity in 148 aa overlap). Also highly similar to others e.g. Q9KXR0|SC9C5.14 from Streptomyces coelicolor (142 aa), FASTA scores: opt: 358,E(): 2.7e-16, (45.0% identity in 140 aa overlap); P54520|NUSB_BACSU from Bacillus subtilis (131 aa), FASTA scores: opt: 315, E(): 1.5e-13, (39.55% identity in 129 aa overlap); O83979|NUSB_TREPA|TP1015 from Treponema pallidum (141 aa), FASTA scores: opt: 268, E(): 1.6e-10, (36.95% identity in 138 aa overlap); etc. BELONGS TO THE NUSB FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28250512825521-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2562c|nusB
MSDRKPVRGRHQARKRAVDLLFEAEVRGISAAEVVDTRAALAEAKPDIARLHPYTAAVARGVSEHAAHIDDLITAHLRGWTLDRLPAVDRAILRVSVWELLHAADVPEPVVVDEAVQLAKELSTDDSPGFVNGVLGQVMLVTPQLRAAAQAVRGGA
Bibliography
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