Gene Mb2595
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | LONG CONSERVED HYPOTHETICAL PROTEIN [FIRST PART] |
| Comments | Mb2595, -, len: 533 aa. Equivalent to 5' end of Rv2566, len: 1140 aa, from Mycobacterium tuberculosis strain H37Rv, (99.6% identity in 531 aa overlap). Long conserved hypothetical protein, equivalent to O53120|ML2678 OR MLCB1913.12 HYPOTHETICAL PROTEIN from Mycobacterium leprae (1000 aa), FASTA scores: opt: 760,E(): 7.1e-38, (50.2% identity in 1128 aa overlap); and middle part equivalent to Q9ZB40 72.2 KDA PROTEIN (FRAGMENT) from Mycobacterium leprae (644 aa), FASTA scores: opt: 1017, E(): 1.5e-65, (45.65% identity in 655 aa overlap). Also highly similar to Q98HG6|MLL2877 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (1119 aa), FASTA scores: opt: 1413, E(): 3.7e-77,(52.4% identity in 1148 aa overlap); and N-terminus shows similarity with other proteins e.g. Q9HUN8|PA4926 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (311 aa),FASTA scores: opt: 278, E(): 3e-09, (29.95% identity in 284 aa overlap); and upstream ORF Q50652|YP69_MYCTU|Rv2569c|MT2645|MTCY227.32 CONSERVED HYPOTHETICAL PROTEIN from Mycobacterium tuberculosis (314 aa), FASTA scores: opt: 252, E(): 1.1e-07, (28.9% identity in 315 aa overlap). Equivalent to AAK46955 from Mycobacterium tuberculosis strain CDC1551 (1156 aa) but shorter 16 aa. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, Rv2566 exists as a single gene. In Mycobacterium bovis, a frameshift due to a 2 bp deletion (gc-*) splits Rv2566 into 2 parts, Mb2595 and Mb2596. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2853824 | 2855425 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2595|Mb2595
MPLRPTQVSSTGRTRCAGRSGVISSAAMSIKVALEHRTSYTFDRLVRVYPHIVRLRPAPHSRTSIEAYSLRIEPADHFINWQQDALGNFLARLVFPNPMRQLRITVGLIADLKVINPFDFFIEDWAEIWPCAGMAYPKALADDLRPYLRPVDEDGDGSGPGELTQAWVRNFTVPDGTRTIDFLVALNRAINADVGYCVRMEPGVQTPDFTLRTGVGSCRDSAWLLVSILRQFGLAARFVSGYLVQLASDIEALDGPSGPAADFTDLHAWSEAYIPGAGWIGLDPTSGLLAGEGHIPLAATPHPASAAPISGGTDVCDTVLEFSNTVTRVHEDPRVTLPYTDESWKTICEVGQRVDERLAAADVRLTVGGEPTFVSVDNQVAEEWRTAADGPHKRERASDLAARLKAVWAPQGLIHRGQGRWYPGEPLPRWQIALYWRTDGRPLWTNDALLADPWGAPPADPVDDDAAYRVLAGIADGLGLPISQVRPAYEDPLSRLAAAVRMPAGDPVESGDDLGCDTNPDTPTGRAALLAPR
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