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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable glutamine amidotransferase snop
CommentsMb2636c, -, len: 198 aa. Equivalent to Rv2604c,len: 198 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 198 aa overlap). Conserved hypothetical protein, equivalent (but shorter 21 aa) to Q49637|HISH|B1177_C1_149 HISH PROTEIN (BELONGS TO THE YFL060C/YAAE/HI1648 FAMILY) (alias Q9CCT5|ML0474 HYPOTHETICAL PROTEIN 223 aa) from Mycobacterium leprae (219 aa), FASTA scores: opt: 1069, E(): 1.7e-60, (83.35% identity in 198 aa overlap). Also highly similar to hypothetical proteins or amidotransferases e.g. Q9L287|SCL2.12c HYPOTHETICAL 21.5 KDA PROTEIN from Streptomyces coelicolor (202 aa), FASTA scores: opt: 702,E(): 2.3e-37, (56.75% identity in 192 aa overlap); P37528|YAAE_BACSU HYPOTHETICAL 21.4 KDA PROTEIN from Bacillus subtilis (196 aa), FASTA scores: opt: 608, E(): 1.9e-31, (48.7% identity in 189 aa overlap); Q9KGN5|BH0023 AMIDOTRANSFERASE from Bacillus halodurans (196 aa), FASTA scores: opt: 583, E(): 7.4e-30, (48.7% identity in 195 aa overlap); etc. Also some similarity with several proteins from Mycobacterium tuberculosis e.g. O06589|HIS5_MYCTU|Rv1602|MT1638|MTCY336.02c AMIDOTRANSFERASE (EC 2.4.2.-) (206 aa), FASTA scores: opt: 154, E(): 0.00036, (30.6% identity in 193 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS28991502899746-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2636c|snop
MSVPRVGVLALQGDTREHLAALRECGAEPMTVRRRDELDAVDALVIPGGESTTMSHLLLDLDLLGPLRARLADGLPAYGSCAGMILLASEILDAGAAGRQALPLRAMNMTVRRNAFGSQVDSFEGDIEFAGLDDPVRAVFIRAPWVERVGDGVQVLARAAGHIVAVRQGAVLATAFHPEMTGDRRIHQLFVDIVTSAA
      
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