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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductCONSERVED HYPOTHETICAL PROTEIN
CommentsMb2647, -, len: 75 aa. Equivalent to Rv2614A, len: 75 aa, from Mycobacterium tuberculosis strain H37Rv,(98.7% identity in 75 aa overlap). Conserved hypothetical protein. The region from aa 10-35 is similar to part of C-terminal part of several TRIOSEPHOSPHATE ISOMERASES (EC 5.3.1.1) e.g. P46711|TPIS_MYCLE|TPIA|TPI|ML0572|B1496_C1_127 from Mycobacterium leprae (261 aa), FASTA scores: opt: 112,E(): 0.95, (60.0% identity in 25 aa overlap); and O08408|TPIS_MYCTU|TPIA|TPI|Rv1438|MT1482|MTCY493.16c from Mycobacterium tuberculosis (261 aa), FASTA scores: opt: 104, E(): 3.3, (60.0% identity in 25 aa overlap); P19583|TPIS_CORGL|TPIA|TPI from Corynebacterium glutamicum (Brevibacterium flavum) (259 aa), FASTA scores: opt: 100,E(): 6, (45.45% identity in 33 aa overlap); etc. TRIOSEPHOSPHATE ISOMERASES PLAY AN IMPORTANT ROLE IN SEVERAL METABOLIC PATHWAYS (CATALYTIC ACTIVITY: D-GLYCERALDEHYDE 3-PHOSPHATE = DIHYDROXY-ACETONE PHOSPHATE).
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29108332911060+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2647|Mb2647
MGDRYRAGDRVLYGGSMSPKDVDDLATQQDVDDGQSIERRWTGSGQRRWRRSPPTGHYRSNSQIQVWISGAGRLR
      
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