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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSMEMBRANE PROTEIN DEDA
CommentsMb2670, dedA, len: 218 aa. Equivalent to Rv2637,len: 218 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 218 aa overlap). Possible dedA,transmembrane protein, equivalent to Q49642|YQ37_MYCLE|ML0467|MLCL581.27|B1177_C2_172/B1177_C1_ 140 HYPOTHETICAL 23.1 KDA PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN, BELONGS TO THE DEDA FAMILY) from Mycobacterium leprae (214 aa), FASTA scores: opt: 1160,E(): 4.4e-64, (82.75% identity in 209 aa overlap); and O69601|Y364_MYCLE|ML0287|MLCB4.30 HYPOTHETICAL PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) (222 aa), FASTA scores: opt: 292, E(): 6.6e-11, (32.25% identity in 189 aa overlap). Also highly similar to other membrane proteins e.g. CAC42863|SCBAC36F5.27c PUTATIVE INTEGRAL MEMBRANE from Streptomyces coelicolor (211 aa), FASTA scores: opt: 837, E(): 2.6e-44, (59.2% identity in 201 aa overlap); Q55705|Y232_SYNY3|SLR0232 POTENTIAL INTEGRAL MEMBRANE PROTEIN from Synechocystis sp. strain PCC 6803 (218 aa),FASTA scores: opt: 415, E(): 1.9e-18, (37.85% identity in 206 aa overlap); Q9RV63|DR1167 DEDA PROTEIN from Deinococcus radiodurans (200 aa); P09548|DEDA_ECOLI|B2317|Z3579|ECS3201 DEDA PROTEIN (DSG-1 PROTEIN) from Escherichia coli strains K12 and O157:H7 (219 aa), BLAST scores: 178, E(): 1.8e-13, Identities = 53/175 (30%); etc. Also similar to O06314|Y364_MYCTU|Rv0364|MT0380|MTCY13E10.26 HYPOTHETICAL 24.5 KDA PROTEIN (POTENTIAL INTEGRAL MEMBRANE PROTEIN) from Mycobacterium tuberculosis (227 aa), FASTA scores: opt: 293, E(): 5.8e-11, (35.85% identity in 184 aa overlap). BELONGS TO THE DEDA FAMILY.
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29310482931704+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2670|dedA
MDVEALLQSIPPLMVYLVVGAVVGIESLGIPLPGEIVLVSAAVLSSHPELAVNPIGVGGAAVIGAVVGDSIGYSIGRRFGLPLFDRLGRRFPKHFGPGHVALAERLFNRWGVRAVFLGRFIALLRIFAGPLAGALKMPYPRFLAANVTGGICWAGGTTALVYFAGMAAQHWLERFSWIALVIAVIAGITAAILLRERTSRAIAELEAEHCRKAGTTAA
      
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