Gene Mb2675 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2675
Gene length381 bp
IdentifierMb2675
Location 2933995 bp
Protein summary information
Molecular mass13111.2 Da
Isoelectric point7.5097
Protein length126 amino acids
Orthologs
M. tuberculosis H37RvRv2642
M. tuberculosis MTBC0mtbc0_002812
Cross-references
InterProIPR001845, IPR011991, IPR018334
UniProtKB/TrEMBLQ7TY65
SWISS-MODELA0A1R3Y1T1
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY ARSR-FAMILY)
CommentsMb2675, -, len: 126 aa. Equivalent to Rv2642, len: 126 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 126 aa overlap). Possible transcriptional regulator, arsR family, highly similar to many e.g. Q9X8X8|SCH35.28c PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces coelicolor (122 aa), FASTA scores: opt: 390, E(): 3.7e-19, (56.55% identity in 122 aa overlap); Q9L220|SC1A2.21 PUTATIVE ARSR-FAMILY TRANSCRIPTIONAL from Streptomyces coelicolor (119 aa),FASTA scores: opt: 378, E(): 2.3e-18, (59.8% identity in 97 aa overlap); Q9L1V5|SC4A9.07 PUTATIVE ARSR-FAMILY TRANSCRIPTIONAL REGULATOR from Streptomyces coelicolor (117 aa), FASTA scores: opt: 359, E(): 4.1e-17, (56.9% identity in 116 aa overlap); P52144|ARR2_ECOLI|ARSR from Escherichia coli (117 aa), FASTA scores: opt: 202, E(): 1e-06, (39.8% identity in 88 aa overlap); etc. Also similar to downstream ORF P71939|Rv2640c|MTCY441.10c PUTATIVE TRANSCRIPTIONAL REGULATORY PROTEIN from Mycobacterium tuberculosis (119 aa), FASTA scores: opt: 237, E(): 5e-09, (38.55% identity in 109 aa overlap); and others from Mycobacterium tuberculosis e.g. O05840|Rv2358|MTCY27.22c. Contains PS00846 Bacterial regulatory proteins, arsR family signature. Contains helix-turn-helix motif at aa 58-79 (Score 1112, +2.97 SD). BELONGS TO THE ARSR FAMILY OF TRANSCRIPTIONAL REGULATORS.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29339952934375+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2675|Mb2675
MSNLHPLPEVASCVVAPLVREPLNPPAAAEMAARFKALADPVRLQLLSSVASRAGGEACVCDISAGVEVSQPTISHHLKVLRDAGLLTSRRRASWVYYAVVPEALTVLSNLLSVHADAAPALGAPA
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