Gene Mb2704 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namearsB1
Gene length1287 bp
IdentifierMb2704
Location 2958619 bp
Protein summary information
Molecular mass45269.8 Da
Isoelectric point6.0839
Protein length428 amino acids
Cross-references
InterProIPR000802, IPR004680
UniProtKB/TrEMBLQ7TY42
SWISS-MODELA0A1R3Y1W7
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSB1
CommentsMb2704, arsB1, len: 428 aa. Equivalent to Rv2685,len: 428 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 428 aa overlap). Probable arsB1,arsenic-transport integral membrane protein, equivalent to P46838|AG45_MYCLE|ML1036 46 KDA PROBABLE INTEGRAL MEMBRANE PROTEIN (antigen 45, a transmembrane protein related to arsenical pumps) from Mycobacterium leprae (429 aa), FASTA scores: opt: 2048, E(): 7.3e-120, (74.25% identity in 427 aa overlap); and downstream ORF O07186|YQ84_MYCTU|ARSA|Rv2684|MT2758|MTCY05A6.05 PROBABLE INTEGRAL MEMBRANE PROTEIN ARSA from Mycobacterium tuberculosis (429 aa), FASTA scores: opt: 2154, E(): 1.9e-126, (76.8% identity in 427 aa overlap). Also highly similar to other proteins e.g. O59575|PH1912 HYPOTHETICAL 46.0 KDA PROTEIN from Pyrococcus horikoshii (424 aa),FASTA scores: opt: 1075, E(): 1.9e-59, (43.55% identity in 427 aa overlap); Q9UY19|PAB1107 TRANSPORT PROTEIN from Pyrococcus abyssi (425 aa), FASTA scores: opt: 1062, E(): 1.3e-58, (41.8% identity in 428 aa overlap); Q9KDI2|BH1231 HYPOTHETICAL 46.0 KDA PROTEIN from Bacillus halodurans (428 aa), FASTA scores: opt: 993, E(): 2.4e-54, (39.55% identity in 430 aa overlap); etc. BELONGS TO THE NADC/P/PHO87 FAMILY OF TRANSPORTERS, P SUBFAMILY. Note that previously known as arsB.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29586192959905+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2704|arsB1
MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFYSHEAGIDWDVIFLLLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMILLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVAEVFASNVGGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLLGSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHIQPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTGVVEQLARAATELTGGNELLTVGLILGISAPVSGIIDNIPYVATMTPIVTELVAAMPGHVHPDTFWWALALSADFGGNLTAVGASANVVMLGIARRSCTPISFWKFTRKGAVVTAVSLVLSAVYLWLRYFVFG
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