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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE ARSENIC-TRANSPORT INTEGRAL MEMBRANE PROTEIN ARSB1
CommentsMb2704, arsB1, len: 428 aa. Equivalent to Rv2685,len: 428 aa, from Mycobacterium tuberculosis strain H37Rv,(99.5% identity in 428 aa overlap). Probable arsB1,arsenic-transport integral membrane protein, equivalent to P46838|AG45_MYCLE|ML1036 46 KDA PROBABLE INTEGRAL MEMBRANE PROTEIN (antigen 45, a transmembrane protein related to arsenical pumps) from Mycobacterium leprae (429 aa), FASTA scores: opt: 2048, E(): 7.3e-120, (74.25% identity in 427 aa overlap); and downstream ORF O07186|YQ84_MYCTU|ARSA|Rv2684|MT2758|MTCY05A6.05 PROBABLE INTEGRAL MEMBRANE PROTEIN ARSA from Mycobacterium tuberculosis (429 aa), FASTA scores: opt: 2154, E(): 1.9e-126, (76.8% identity in 427 aa overlap). Also highly similar to other proteins e.g. O59575|PH1912 HYPOTHETICAL 46.0 KDA PROTEIN from Pyrococcus horikoshii (424 aa),FASTA scores: opt: 1075, E(): 1.9e-59, (43.55% identity in 427 aa overlap); Q9UY19|PAB1107 TRANSPORT PROTEIN from Pyrococcus abyssi (425 aa), FASTA scores: opt: 1062, E(): 1.3e-58, (41.8% identity in 428 aa overlap); Q9KDI2|BH1231 HYPOTHETICAL 46.0 KDA PROTEIN from Bacillus halodurans (428 aa), FASTA scores: opt: 993, E(): 2.4e-54, (39.55% identity in 430 aa overlap); etc. BELONGS TO THE NADC/P/PHO87 FAMILY OF TRANSPORTERS, P SUBFAMILY. Note that previously known as arsB.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29586192959905+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2704|arsB1
MSIIAITVFVAGYALIASDRVSKTRVALTCAAIMVGAGIVGSDDVFYSHEAGIDWDVIFLLLGMMIIVSVLRHTGVFEYVAIWAVKRANAAPLRIMILLVLVTALGSALLDNVTTVLLIAPVTLLVCDRLGVNSTPFLVAEVFASNVGGAATLVGDPPNIIIASRAGLTFNDFLIHMAPAVLVVMIALIGLLPWLLGSVTAEPDRVADVLSLNEREAIHDRGLLIKCGVVLVLVFAAFIAHPVLHIQPSLVALLGAGVLVRFSGLERSDYLSSVEWDTLLFFAGLFVMVGALVKTGVVEQLARAATELTGGNELLTVGLILGISAPVSGIIDNIPYVATMTPIVTELVAAMPGHVHPDTFWWALALSADFGGNLTAVGASANVVMLGIARRSCTPISFWKFTRKGAVVTAVSLVLSAVYLWLRYFVFG
      
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