Gene Mb2708c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2708c
Gene length1218 bp
IdentifierMb2708c
Location 2962481 bp
Protein summary information
Molecular mass43241.9 Da
Isoelectric point7.0198
Protein length405 amino acids
Orthologs
M. tuberculosis H37RvRv2689c
M. tuberculosis MTBC0mtbc0_002863
Cross-references
InterProIPR002792, IPR010280, IPR012340
UniProtKB/TrEMBLQ7TY38
SWISS-MODELA0A1R3Y2Q7
General annotation
TypeCDS
FunctionUnknown
Productconserved alanine and valine and glycine rich protein
CommentsMb2708c, -, len: 405 aa. Equivalent to Rv2689c,len: 405 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 405 aa overlap). Conserved hypothetical ala-, val-, gly-rich protein, similar to O54099|SC10A5.06 HYPOTHETICAL 49.5 KDA PROTEIN from Streptomyces coelicolor (458 aa), FASTA scores: opt: 455,E(): 2.7e-20, (38.35% identity in 417 aa overlap); and shows weak similarity in part with several methyltransferases (EC 2.1.1.-) e.g. Q9X0H9|TM1094 PUTATIVE RNA METHYLTRANSFERASE from Thermotoga maritima (439 aa), FASTA scores: opt: 306, E(): 3e-11, (25.9% identity in 436 aa overlap); AK79403|CAC1435 S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASES from Clostridium acetobutylicum (456 aa), FASTA scores: opt: 294, E(): 1.6e-10, (23.4% identity in 449 aa overlap); Q9A8M7|CC1326 RNA METHYLTRANSFERASE from Caulobacter crescentus (415 aa), FASTA scores: opt: 247, E(): 1.1e-07,(28.4% identity in 433 aa overlap); etc. Equivalent to AAK47078 from Mycobacterium tuberculosis strain CDC1551 (434 aa) but shorter 29 aa. Other less probable starts possible.
Functional categoryConserved hypotheticals
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29624812963698-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2708c|Mb2708c
MTRAGDDAVNLTLVTGAPANGGSCVAHHEGRVVFVRYALPGERVRARVTAQRGSYWHAEAFEVIDPSPDRIGSLCSIAGADGAGCCDLAFAAPEAARTLKAQVVANQLERLGRHSWQGEAQPLSDAGPTGWRIRVRLDVGADRRPGFHRYHSGELVTDLDCGQLPVGMLDGLVAADWPPEAQLYVALDDDGERHVVCSVRQGPRNRTRTVTNVVEGAYHAHQRVHRRSWRVPVTAFWQAHRDAAAVYSDLIADWAQPAPGMTAWDLYGGAGVFAAVLGEAVGESGRVLTVDTSRLASGAARAALVDLPQVEVVTGSVRRVLAVQPAGADLAVLDPPRSGAGREVVDLLAGAGVPRLIHIGCEAASFARDIGLYRGHGYAVEKIKVFDAFPLTHYVECVALLTRKV
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