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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable deoxyuridine 5'-triphosphate nucleotidohydrolase dut (dutpase) (dutp pyrophosphatase) (deoxyuridine 5'-triphosphatase) (dutp diphosphatase) (deoxyuridine-triphosphatase)
CommentsMb2716c, dut, len: 154 aa. Equivalent to Rv2697c,len: 154 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 154 aa overlap). Probable dut,deoxyuridine 5'-triphosphate nucleotidohydrolase (EC 3.6.1.23), equivalent to Q49992|DUT_MYCLE|ML1028 DEOXYURIDINE 5'-TRIPHOSPHATE NUCLEOTIDOHYDROLASE from Mycobacterium leprae (154 aa), FASTA scores: opt: 928,E(): 2.1e-51, (90.25% identity in 154 aa overlap). Also highly similar to others e.g. O54134|DUT_STRCO|SC2E9.09 from Streptomyces coelicolor (183 aa), FASTA scores: opt: 534, E(): 1.2e-26, (56.1% identity in 148 aa overlap); O66592|DUT_AQUAE|AQ_220 from Aquifex aeolicus (150 aa),FASTA scores: opt: 398, E(): 3.3e-18, (48.05% identity in 152 aa overlap); Q9X3X5|DUT_ZYMMO from Zymomonas mobilis (146 aa), FASTA scores: opt: 396, E(): 4.4e-18, (49.0% identity in 147 aa overlap); etc. BELONGS TO THE DUTPASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29703192970783-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2716c|dut
MSTTLAIVRLDPGLPLPSRAHDGDAGVDLYSAEDVELAPGRRALVRTGVAVAVPFGMVGLVHPRSGLATRVGLSIVNSPGTIDAGYRGEIKVALINLDPAAPIVVHRGDRIAQLLVQRVELVELVEVSSFDEAGLASTSRGDGGHGSSGGHASL
      
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