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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productinositol-1-monophosphatase suhb
CommentsMb2720c, suhB, len: 290 aa. Equivalent to Rv2701c,len: 290 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 290 aa overlap). Possible suhB,extragenic suppressor protein, equivalent to P46813|SUHB_MYCLE|SUHB|SSYA|ML1024 EXTRAGENIC SUPPRESSOR PROTEIN from Mycobacterium leprae (291 aa), FASTA scores: opt: 1424, E(): 4.9e-78, (77.55% identity in 294 aa overlap). Similar (except at N-terminus) to others e.g. O54128|SUHB from Streptomyces coelicolor (209 aa), FASTA scores: opt: 560, E(): 1.7e-26, (46.95% identity in 213 aa overlap); Q9CNV8|SUHB|PM0315 from Pasteurella multocida (267 aa), FASTA scores: opt: 479, E(): 1.5e-21, (39.3% identity in 234 aa overlap); P44333|SUHB_HAEIN|HI0937 from Haemophilus influenzae (267 aa), FASTA scores: opt: 438,E(): 4.1e-19, (34.7% identity in 248 aa overlap); P22783|SUHB_ECOLI|SSYA|B2533 from Escherichia coli strain K12 (267 aa), FASTA scores: opt: 419, E(): 5.7e-18,(34.45% identity in 267 aa overlap); etc. And also similar to putative myo-inositol-1(or 4)-monophosphatases e.g. Q9S1M1|SPCA from Streptoverticillium netropsis (Streptoverticillium flavopersicus) (266 aa), FASTA scores: opt: 556, E(): 3.6e-26, (45.4% identity in 240 aa overlap); Q9S3X5|SPCA from Streptomyces spectabilis (264 aa), FASTA scores: opt: 502, E(): 6.1e-23, (46.05% identity in 265 aa overlap); CAC47357 from Rhizobium meliloti (Sinorhizobium meliloti) (266 aa), FASTA scores: opt: 452, E(): 6e-20, (38.5% identity in 244 aa overlap); etc. Equivalent to AAK47090 from Mycobacterium tuberculosis strain CDC1551 (277 aa) but longer 13 aa. Contains PS00630 Inositol monophosphatase family signatures 1 and 2 (PS00629 and PS00630). BELONGS TO THE INOSITOL MONOPHOSPHATASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS29724992973371-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2720c|suhB
MTRPDNEPARLRSVAENLAAEAAAFVRGRRAEVFGISRAGDGDGAVRAKSSPTDPVTVVDTDTERLLRDRLAQLRPGDPILGEEGGGPADVTATPSDRVTWVLDPIDGTVNFVYGIPAYAVSIGAQVGGITVAGAVADVAARTVYSAATGLGAHLTDERGRHVLRCTGVDELSMALLGTGFGYSVRCREKQAELLAHVVPLVRDVRRIGSAALDLCMVAAGRLDAYYEHGVQVWDCAAGALIAAEAGARVLLSTPRAGGAGLVVVAAAPGIADELLAALQRFNGLEPIPD
      
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