Gene Mb2750
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | conserved alanine and arginine rich protein |
| Comments | Mb2750, -, len: 450 aa. Equivalent to Rv2731, len: 450 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 450 aa overlap). Conserved hypothetical ala-, arg-rich protein, highly similar in part to Q49849|B2235_F2_77 HYPOTHETICAL PROTEIN from Mycobacterium leprae (266 aa), FASTA scores: opt: 368,E(): 1e-10, (73.5% identity in 83 aa overlap); and Q9KXN9|SC9C5.35 HYPOTHETICAL 6.5 KDA PROTEIN (FRAGMENT) from Streptomyces coelicolor (58 aa), FASTA scores: opt: 214, E(): 0.00065, (51.7% identity in 58 aa overlap). Also similar to Q9L296|SCL2.01 HYPOTHETICAL 37.4 KDA PROTEIN (FRAGMENT) from Streptomyces coelicolor (328 aa), FASTA scores: opt: 843, E(): 3.7e-33, (45.95% identity in 296 aa overlap) (but N-terminus shorter); and shows some similarity with other proteins e.g. Q26938 KINETOPLAST-ASSOCIATED PROTEIN (KAP) from Trypanosoma cruzi (1052 aa), FASTA scores: opt: 223, E(): 0.0022,(30.3% identity in 297 aa overlap). Start site chosen by RBS and to avoid overlap, although there are several other possible start sites further upstream. |
| Functional category | Conserved hypotheticals |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 2999662 | 3001014 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2750|Mb2750
MTADEPRSDDSSGSAPQPAATPVPRPGPRPGPRPVPRPTSYPVGAHPPSDPHRFGRIDDDGTVWLVSASGERIVGSWQAGDPEAAFAHFGRRFDDLSTEIMLMDERLASGTGDARKIKAHAIALAETLPTACVLGDVDALADRLTSIRDRAEVIAAADRSRREEHRAAQTARKEALAAEAEELAANATQWKVAGDRLRAILDEWKTISGVDRKVDDALWKRYSTARDTFNRRRGSHFAELDRERSGVRQSKERLCERAEELSESTDWTATSAEFRKLLADWKAAGRASKDVDDALWRRFKAAQDSFFTARNAATAEKEAELRANADAKEALLAEAERLDTTNHEAARAALRSIAEKWDAIGKVSRERAAELERRLRAVEKKVREAGEADWSDPQARARAEQFRARAEQFEHQAEKAAAAGRTKEADEAKANAEQWRQWAEAAADALTRRP
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