Gene Mb2756c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | RECA PROTEIN (RECOMBINASE A) [CONTAINS: ENDONUCLEASE PI-MTUI (MTU RECA INTEIN)]. |
| Comments | Mb2756c, recA, len: 790 aa. Equivalent to Rv2737c,len: 790 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 790 aa overlap). recA, recombinase A (EC 3.1.-.-), (see citations below), equivalent to Q59560|RECA_MYCSM RECA PROTEIN from Mycobacterium smegmatis (349 aa), FASTA scores: opt: 1495, E(): 1.9e-79,(93.15% identity in 249 aa overlap); and P35901|RECA_MYCLE|ML0987 RECA PROTEIN from Mycobacterium leprae (711 aa), FASTA scores: opt: 1217, E(): 4.5e-63,(46.7% identity in 814 aa overlap). Also highly similar to many e.g. Q9REV6|RECA_AMYMD from Amycolatopsis mediterranei (Nocardia mediterranei) (348 aa), FASTA scores: opt: 1450, E(): 7.6e-77, (89.25% identity in 251 aa overlap); P42442|RECA_CORGL from Corynebacterium glutamicum (Brevibacterium flavum) (376 aa), FASTA scores: opt: 1355, E(): 2.6e-71, (76.55% identity in 273 aa overlap); P41054|RECA_STRAM from Streptomyces ambofaciens (372 aa), FASTA scores: opt: 1347, E(): 7.6e-71, (82.1% identity in 246 aa overlap); etc. Contains PS00017 ATP/GTP-binding site motif A (P-loop), PS00321 recA signature, and PS00881 Protein splicing signature. BELONGS TO THE RECA FAMILY. THIS PROTEIN UNDERGOES A PROTEIN SELF SPLICING THAT INVOLVES A POST-TRANSLATIONAL EXCISION OF THE INTERVENING REGION (INTEIN) FOLLOWED BY PEPTIDE LIGATION. BELONGS TO THE HOMING ENDONUCLEASE FAMILY IN THE INTEIN SECTION. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3005688 | 3008060 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2756c|recA
MTQTPDREKALELAVAQIEKSYGKGSVMRLGDEARQPISVIPTGSIALDVALGIGGLPRGRVIEIYGPESSGKTTVALHAVANAQAAGGVAAFIDAEHALDPDYAKKLGVDTDSLLVSQPDTGEQALEIADMLIRSGALDIVVIDSVAALVPRAELEGEMGDSHVGLQARLMSQALRKMTGALNNSGTTAIFINQLRDKIGVMFGSPETTTGGKALKFYASVRMDVRRVETLKDGTNAVGNRTRVKVVKNKCLAEGTRIFDPVTGTTHRIEDVVDGRKPIHVVAAAKDGTLHARPVVSWFDQGTRDVIGLRIAGGAIVWATPDHKVLTEYGWRAAGELRKGDRVAQPRRFDGFGDSAPIPADHARLLGYLIGDGRDGWVGGKTPINFINVQRALIDDVTRIAATLGCAAHPQGRISLAIAHRPGERNGVADLCQQAGIYGKLAWEKTIPNWFFEPDIAADIVGNLLFGLFESDGWVSREQTGALRVGYTTTSEQLAHQIHWLLLRFGVGSTVRDYDPTQKRPSIVNGRRIQSKRQVFEVRISGMDNVTAFAESVPMWGPRGAALIQAIPEATQGRRRGSQATYLAAEMTDAVLNYLDERGVTAQEAAAMIGVASGDPRGGMKQVLGASRLRRDRVQALADALDDKFLHDMLAEELRYSVIREVLPTRRARTFDLEVEELHTLVAEGVVVHNCSPPFKQAEFDILYGKGISREGSLIDMGVDQGLIRKSGAWFTYEGEQLGQGKENARNFLVENADVADEIEKKIKEKLGIGAVVTDDPSNDGVLPAPVDF
Bibliography
No article yet recorded
