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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable l-glutamate alpha-n-acetyltranferase arga (alpha-n-acetylglutamate synthase)
CommentsMb2768, -, len: 174 aa. Equivalent to Rv2747, len: 174 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 174 aa overlap). Possible transferase (EC 2.-.-.-), equivalent to O05559|ML0978|MLCB33.08 PUTATIVE ACETYLTRANSFERASE from Mycobacterium leprae (180 aa), FASTA scores: opt: 997, E(): 1.2e-57, (86.8% identity in 174 aa overlap). Also similar to various transferases e.g. Q9X8N2|SCE94.27c PUTATIVE ACETYLTRANSFERASE from Streptomyces coelicolor (169 aa), FASTA scores: opt: 656,E(): 1.3e-35, (60.35% identity in 164 aa overlap); C-terminus of Q9K3D6|ARGH(A) ARGININOSUCCINASE AND N-ACETYLGLUTAMATE SYNTHASE from Moritella sp. 2693 (629 aa), FASTA scores: opt: 243, E(): 2e-08, (31.95% identity in 144 aa overlap); C-terminus of Q9JW21|ARGA OR NMA0580 PUTATIVE ACETYLGLUTAMATE SYNTHASE from Neisseria meningitidis serogroup A (436 aa), FASTA scores: opt: 201,E(): 7.8e-06, (32.75% identity in 119 aa overlap); etc. Also similar to hypothetical proteins e.g. O67372|AQ_1359 HYPOTHETICAL 21.1 KDA PROTEIN from Aquifex aeolicus (181 aa), FASTA scores: opt: 348, E(): 1.2e-15, (42.35% identity in 137 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30158363016360+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2768|arga
MTERPRDCRPVVRRARTSDVPAIKQLVDTYAGKILLEKNLVTLYEAVQEFWVAEHPDLYGKVVGCGALHVLWSDLGEIRTVAVDPAMTGHGIGHAIVDRLLQVARDLQLQRVFVLTFETEFFARHGFTEIEGTPVTAEVFDEMCRSYDIGVAEFLDLSYVKPNILGNSRMLLVL
      
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