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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productprobable thymidylate synthase thyx (ts) (tsase)
CommentsMb2775c, -, len: 250 aa. Equivalent to Rv2754c,len: 250 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 250 aa overlap). Conserved hypothetical ala-rich protein, equivalent to Q9CBW3|YF14_MYCLE|ML1514 HYPOTHETICAL 28.0 KDA PROTEIN from Mycobacterium leprae (254 aa), FASTA scores: opt: 1351, E(): 1e-84, (81.5% identity in 254 aa overlap). Also highly similar to 40111|YDAP_CORGL from Corynebacterium glutamicum (Brevibacterium flavum) (250 aa), FASTA scores: opt: 1071, E(): 1.2e-65, (62.85% identity in 245 aa overlap); Q05259|VG48_BPML5 GENE 48 PROTEIN (GP48) from Mycobacteriophage L5 (243 aa),, FASTA scores: opt: 610,E(): 3.2e-34, (49.55% identity in 220 aa overlap); O64238|VG48_BPMD2 GENE 48 PROTEIN (GP48) from Mycobacteriophage D29 (235 aa), FASTA scores: opt: 593,E(): 4.5e-33, (46.95% identity in 245 aa overlap); etc. BELONGS TO THE THY1 FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30237673024519-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2775c|thyx
MAETAPLRVQLIAKTDFLAPPDVPWTTDADGGPALVEFAGRACYQSWSKPNPKTATNAGYLRHIIDVGHFSVLEHASVSFYITGISRSCTHELIRHRHFSYSQLSQRYVPEKDSRVVVPPGMEDDADLRHILTEAADAARATYSELLAKLEAKFADQPNAILRRKQARQAARAVLPNATETRIVVTGNYRAWRHFIAMRASEHADVEIRRLAIECLRQLAAVAPAVFADFEVTTLADGTEVATSPLATEA
      
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