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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
Productpossible toxin vapc42. contains pin domain.
CommentsMb2780c, -, len: 131 aa. Equivalent to Rv2759c,len: 131 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 131 aa overlap). Conserved hypothetical protein, highly similar to three M. tuberculosis hypothetical proteins O07769|Y609_MYCTU|Rv0609|MT0638|MTCY19H5.13c (133 aa),FASTA scores: opt: 364, E(): 5.1e-18, (49.6% identity in 131 aa overlap); P96914|Y624_MYCTU|Rv0624|MT0652|MTCY20H10.05 (131 aa),FASTA scores: opt: 324, E(): 2.9e-15, (42.85% identity in 126 aa overlap); and Q10874|YJ82_MYCTU|Rv1982c|MT2034|MTCY39.37 (139 aa), FASTA scores: opt: 271, E(): 1.4e-11, (38.6% identity in 127 aa overlap). Also similar to other hypothetical proteins from other bacteria e.g. CAC45376|SMC00900 CONSERVED HYPOTHETICAL PROTEIN from Rhizobium meliloti (Sinorhizobium meliloti) (128 aa), FASTA scores: opt: 286,E(): 1.2e-12, (39.55% identity in 129 aa overlap); Q981I7|MLL9357 HYPOTHETICAL PROTEIN from Rhizobium loti (Mesorhizobium loti) (131 aa), FASTA scores: opt: 257,E(): 1.2e-10, (36.35% identity in 132 aa overlap); Q9AAG1|CC0639 HYPOTHETICAL PROTEIN from Caulobacter crescentus (131 aa), FASTA scores: opt: 217, E(): 6.9e-08,(33.35% identity in 132 aa overlap); etc.
Functional categoryVirulence, detoxification, adaptation
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS30274493027844-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2780c|vapc42
MIVDTSAIVAIVSGESGAQVLKEALERSPNSRMSAPNYVELCAIMQRRDRPEISRLVDRLLDDYGIQVEAVDADQARVAAQAYRDYGRGSGHPARLNLGDTYSYALAQVTGEPLLFRGDDFTHTDIRPACT
      
Bibliography
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