Gene Mb2860c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE Sn-GLYCEROL-3-PHOSPHATE TRANSPORT INTEGRAL MEMBRANE PROTEIN ABC TRANSPORTER UGPAA [FIRST PART] |
| Comments | Mb2860c, ugpAa, len: 123 aa. Similar to 5' end of Rv2835c, len: 303 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 85 aa overlap). Probable ugpA, Sn-glycerol-3-phosphate transport integral membrane protein ABC transporter (see citation below), similar to various permeases e.g. Q9RK71|SCF11.19 PROBABLE SUGAR TRANSPORTER INNER MEMBRANE PROTEIN from Streptomyces coelicolor (316 aa), FASTA scores: opt: 643, E(): 3.1e-35,(38.85% identity in 291 aa overlap); Q9KDY4|BH1077 GLYCEROL-3-PHOSPHATE ABC TRANSPORTER (PERMEASE) from Bacillus halodurans (315 aa), FASTA scores: opt: 548, E(): 6.2e-29, (31.5% identity in 295 aa overlap); AAK78407|CAC0427 GLYCEROL-3-PHOSPHATE ABC-TRANSPORTER,PERMEASE COMPONENT from Clostridium acetobutylicum (304 aa), FASTA scores: opt: 538, E(): 2.8e-28, (29.1% identity in 292 aa overlap); etc. Contains PS00062 Aldo/keto reductase family signature 2, and PS00402 Binding-protein-dependent transport systems inner membrane comp signature. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis strain H37Rv, ugpA exists as a single gene. In Mycobacterium bovis, a frameshift due to a single base deletion (t-*) splits ugpA into 2 parts, ugpAa and ugpAb. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3098421 | 3098792 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2860c|ugpAa
MAAPQRARLRSSKERVRDYALFVVLVGPNVALLLLFVYRPLADNIRLSFFDWNVSDPSARFVGLSNYTEWFTRSDTRQIVFNTAVSPVPRWSARWCWGWRWRCCSIDRCVDETWCAPLFSRRS
Bibliography
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