Gene Mb2900 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namempt70
Gene length582 bp
IdentifierMb2900
Location 3143546 bp
Protein summary information
Molecular mass19072.5 Da
Isoelectric point4.5425
Protein length193 amino acids
Orthologs
M. tuberculosis H37RvRv2875
M. tuberculosis MTBC0mtbc0_003058
Cross-references
UniProtKB/TrEMBLX2BLT4, P0A669
SWISS-MODELP0A669
General annotation
TypeCDS
FunctionUnknown
Productmajor secreted immunogenic protein mpt70
CommentsMb2900, mpb70, len: 193 aa. Equivalent to Rv2875,len: 193 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 193 aa overlap). mpt70 (alternate gene name: mpb70), major secreted immunogenic protein MPT70 precursor (see citations below). Also similar to downstream ORF Q10790|MP83_MYCTU|MPT83|MPB83|Rv2873|MT2940|MTCY274.04 CELL SURFACE LIPOPROTEIN MPT83 PRECURSOR (LIPOPROTEIN P23) (220 aa), FASTA scores: opt: 806, E(): 1.2e-40, (70.25% identity in 185 aa overlap). BELONGS TO THE MPT70 / MPT83 FAMILY. GENERALLY FOUND AS A MONOMER; HOMODIMER IN CULTURE FLUIDS.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31435463144127+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2900|mpt70
MKVKNTIAATSFAAAGLAALAVAVSPPAAAGDLVGPGCAEYAAANPTGPASVQGMSQDPVAVAASNNPELTTLTAALSGQLNPQVNLVDTLNSGQYTVFAPTNAAFSKLPASTIDELKTNSSLLTSILTYHVVAGQTSPANVVGTRQTLQGASVTVTGQGNSLKVGNADVVCGGVSTANATVYMIDSVLMPPA
Bibliography
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