Gene Mb2903c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | soluble secreted antigen mpt53 precursor |
| Comments | Mb2903c, mpb53, len: 173 aa. Equivalent to Rv2878c,len: 173 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 173 aa overlap). mpt53, secreted protein (contains N-terminal signal sequence) (see citations below). Shows some similarity with several disulfide bond interchange proteins e.g. P43787|THIX_HAEIN THIOREDOXIN-LIKE PROTEIN HI1115 from Haemophilus influenzae (167 aa), FASTA scores: opt: 200, E(): 1.4e-06,(28.9% identity in 135 aa overlap); P52237|TIPB_PSEFL THIOL:DISULFIDE INTERCHANGE PROTEIN TIPB PRECURSOR (CYTOCHROME C BIOGENESIS PROTEIN TIPB) (178 aa), FASTA scores: opt: 184, E(): 1.8e-05, (26.3% identity in 171 aa overlap); etc. Also highly similar to O53924|DSBF|Rv1677|MTV047.12 PUTATIVE LIPOPROTEIN from Mycobacterium tuberculosis (182 aa), FASTA scores: opt: 482, E(): 5.7e-26, (52.8% identity in 142 aa overlap). COULD BE BELONG TO THE THIOREDOXIN FAMILY. Note that also previously known as dsbE. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3145392 | 3145913 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2903c|mpt53
MSLRLVSPIKAFADGIVAVAIAVVLMFGLANTPRAVAADERLQFTATTLSGAPFDGASLQGKPAVLWFWTPWCPFCNAEAPSLSQVAAANPAVTFVGIATRADVGAMQSFVSKYNLNFTNLNDADGVIWARYNVPWQPAFVFYRADGTSTFVNNPTAAMSQDELSGRVAALTS
Bibliography
No article yet recorded
