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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE INTEGRASE/RECOMBINASE XERC
CommentsMb2918c, xerC, len: 298 aa. Equivalent to Rv2894c,len: 298 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 298 aa overlap). Probable xerC,integrase/recombinase, equivalent to Q9CBU0|XERC|ML1600|MLCB250.62 INTEGRASE/RECOMBINASE from Mycobacterium leprae (297 aa), FASTA scores: opt: 1624,E(): 2e-97, (85.15% identity in 296 aa overlap). Also highly similar to others integrases/recombinases (generally xerC and xerD) e.g. Q9HTS4|SSS|PA5280 SITE-SPECIFIC RECOMBINASE from Pseudomonas aeruginosa (303 aa), FASTA scores: opt: 660, E(): 3.2e-35, (41.8% identity in 299 aa overlap); Q9HXQ6|XERD|PA3738 INTEGRASE/RECOMBINASE from Pseudomonas aeruginosa (298 aa), FASTA scores: opt: 656, E(): 5.7e-35, (40.05% identity in 297 aa overlap); Q9KCP0|BH1529 INTEGRASE/RECOMBINASE from Bacillus halodurans (299 aa),FASTA scores: opt: 645, E(): 2.9e-34, (37.35% identity in 300 aa overlap); etc. Also similar to O33200|Rv1701|MTCI125.23 INTEGRASE/RECOMBINASE from Mycobacterium tuberculosis (311 aa), FASTA scores: opt: 646, E(): 2.6e-34, (43.1% identity in 304 aa overlap). BELONGS TO THE 'PHAGE' INTEGRASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31599103160806-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2918c|xerC
MQAILDEFDEYLALQCGRSVHTRRAYLGDLRSLFAFLADRGSSLDALTLSVLRSWLAATAGAGAARTTLARRTSAVKAFTAWAVRRGLLAGDPAARLQVPKARRTLPAVLRQDQALRAMAAAESGAEQGDPLALRDRLIVELLYATGIRVSELCGLDVDDIDTGHRLVRVLGKGNKQRTVPFGQPAADALHAWLVDGRRALVTAESGHALLLGARGRRLDVRQARTAVHQTVAAVDGAPDMGPHGLRHSAATHLLEGGADLRVVQELLGHSSLATTQLYTHVAVARLRAVHERAHPRA
      
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