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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE CONSERVED ALANINE RICH LIPOPROTEIN LPPW
CommentsMb2929, lppW, len: 314 aa. Equivalent to Rv2905,len: 314 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 314 aa overlap). Probable lppW,conserved ala-rich lipoprotein, with slight similarity to beta-lactamases and hypothetical proteins e.g. Q9S1P7|SCJ9A.23 HYPOTHETICAL 36.3 KDA PROTEIN from Streptomyces coelicolor (336 aa), FASTA scores: opt: 222,E(): 2.8e-06, (25.5% identity in 298 aa overlap); O69914|SC3C8.01 PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (302 aa), FASTA scores: opt: 201,E(): 5.1e-05, (24.9% identity in 257 aa overlap); P14559|BLAC_STRAL BETA-LACTAMASE PRECURSOR from Streptomyces albus G (314 aa), FASTA scores: opt: 113,E(): 3.3, (25.2% identity in 278 aa overlap); etc. Has signal peptide and appropriately positioned prokaryotic lipoprotein lipid attachment site: ATTACHED TO THE MEMBRANE BY A LIPID ANCHOR (POTENTIAL).
Functional categoryCell wall and cell processes
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS31711443172088+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2929|lppW
MRARPLTLLTALAAVTLVVVAGCEARVEAEAYSAADRISSRPQARPQPQPVELLLRAITPPRAPAASPNVGFGELPTRVRQATDEAAAMGATLSVAVLDRATGQLVSNGNTQIIATASVAKLFIADDLLLAEAEGKVTLSPEDHHALDVMLQSSDDGAAERFWSQDGGNAVVTQVARRYGLRSTAPPSDGRWWNTISSAPDLIRYYDMLLDGSGGLPLDRAAVIIADLAQSTPTGIDGYPQRFGIPDGLYAEPVAVKQGWMCCIGSSWMHLSTGVIGPERRYIMVIESLQPADDATARATITQAVRTMFPNGRI
      
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