Gene Mb2976
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE METHYLTRANSFERASE (METHYLASE) |
| Comments | Mb2976, -, len: 270 aa. Equivalent to Rv2952, len: 270 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 270 aa overlap). Probable methyltransferase (EC 2.1.1.-), equivalent to Q9CD86|ML0130 HYPOTHETICAL PROTEIN from Mycobacterium leprae (270 aa), FASTA scores: opt: 1584, E(): 6.1e-99,(83.7% identity in 270 aa overlap). Also highly similar to Q9RMN9|MTF2 PUTATIVE METHYLTRANSFERASE from Mycobacterium smegmatis (274 aa), FASTA scores: opt: 902, E(): 3.8e-53,(56.35% identity in 252 aa overlap). Also similar to other methyltransferases e.g. Q9ADL4|SORM O-METHYLTRANSFERASE from Polyangium cellulosum (346 aa), FASTA scores: opt: 390, E(): 1.1e-18, (36.25% identity in 251 aa overlap); Q54303|RAPM METHYLTRANSFERASE from Streptomyces hygroscopicus (317 aa), FASTA scores: opt: 315, E(): 1.1e-13, (40.75% identity in 135 aa overlap); etc. Very similar to C-terminal part of Q50584|Rv1523|MTCY19G5.05c HYPOTHETICAL 37.9 KDA PROTEIN from Mycobacterium tuberculosis (358 aa), FASTA score: opt: 965, E(): 2.7e-57, (60.3% identity in 247 aa overlap). |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3261129 | 3261941 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2976|Mb2976
MAFSRTHSLLARAGSTSTYKRVWRYWYPLMTRGLGNDEIVFINWAYEEDPPMDLPLEASDEPNRAHINLYHRTATQVDLGGKQVLEVSCGHGGGASYLTRTLHPASYTGLDLNQAGIKLCKKRHRLPGLDFVRGDAENLPFDDESFDVVLNVEASHCYPHFRRFLAEVVRVLRPGGYFPYADLRPNNEIAAWEADLAATPLRQLSQRQINAEVLRGIGNNSQKSRDLVDRHLPAFLRFAGREFIGVQGTQLSRYLEGGELSYRMYCFTKD
Bibliography
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