Gene Mb2981 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2981
Gene length828 bp
IdentifierMb2981
Location 3266158 bp
Protein summary information
Molecular mass31046.1 Da
Isoelectric point9.5593
Protein length275 amino acids
Orthologs
M. tuberculosis H37RvRv2957
M. tuberculosis MTBC0mtbc0_003139
Cross-references
UniProtKB/TrEMBLX2BMC2, P0A5A0
SWISS-MODELP0A5A0
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE GLYCOSYL TRANSFERASE
CommentsMb2981, -, len: 275 aa. Equivalent to Rv2957, len: 275 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 275 aa overlap). Possible glycosyl transferase (EC 2.4.1.-); possibly secreted protein. Highly similar to O88109|GSD|GTFD GSD PROTEIN from Mycobacterium avium subsp. silvaticum, Mycobacterium paratuberculosis, and Mycobacterium avium (266 aa), FASTA scores: opt: 1010, E(): 2.5e-62, (68.8% identity in 221 aa overlap). Also some similarity with other proteins and especially glycosyl transferases e.g. Q9AEE4 HYPOTHETICAL 31.4 KDA PROTEIN from Leptospira interrogans (265 aa),FASTA scores: opt: 371, E(): 3.3e-18, (34.43% identity in 212 aa overlap); Q9EXY4 PUTATIVE GLYCOSYL TRANSFERASE from Escherichia coli (248 aa), FASTA scores: opt: 339, E(): 5e-16, (32.4% identity in 210 aa overlap); Q9RCC4 GLYCOSYLTRANSFERASE-LIKE PROTEIN from Yersinia pestis (247 aa), FASTA scores: opt: 333, E(): 1.3e-15, (31.8% identity in 217 aa overlap); Q9EXY1 PUTATIVE GLYCOSYL TRANSFERASE from Escherichia coli (248 aa), FASTA scores: opt: 328,E(): 2.9e-15, (31.9% identity in 210 aa overlap); etc. Equivalent to AAK47357 from Mycobacterium tuberculosis strain CDC1551 (256 aa) but longer 19 aa.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32661583266985+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2981|Mb2981
MVQTKRYAGLTAANTKKVAMAAPMFSIIIPTLNVAAVLPACLDSIARQTCGDFELVLVDGGSTDETLDIANIFAPNLGERLIIHRDTDQGVYDAMNRGVDLATGTWLLFLGADDSLYEADTLARVAAFIGEHEPSDLVYGDVIMRSTNFRWGGAFDLDRLLFKRNICHQAIFYRRGLFGTIGPYNLRYRVLADWDFNIRCFSNPALVTRYMHVVVASYNEFGGLSNTIVDKEFLKRLPMSTRLGIRLVIVLVRRWPKVISRAMVMRTVISWRRRR
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