Gene Mb2982c
in Mycobacterium bovis AF2122/97
General annotation
Type | CDS |
Function | Unknown |
Product | possible glycosyl transferase |
Comments | Mb2982c, -, len: 366 aa. Similar to 5' end of Rv2958c, len: 428 aa, from Mycobacterium tuberculosis strain H37Rv, (83.3% identity in 371 aa overlap). Possible glycosyl transferase (EC 2.4.1.-), highly similar to Q9CD88|ML0128 PUTATIVE GLYCOSYL TRANSFERASE from Mycobacterium leprae (435 aa), FASTA scores: opt: 2116,E(): 5.8e-126, (75.05% identity in 417 aa overlap); and Q9CD91|ML0125 PUTATIVE GLYCOSYL TRANSFERASE from Mycobacterium leprae (438 aa), FASTA scores: opt: 2104,E(): 3.3e-125, (74.65% identity in 418 aa overlap). Also shows some similarity to variety of glycosyl transferases e.g. Q9RYI3 PUTATIVE GLYCOSYLTRANSFERASE from Deinococcus radiodurans (418 aa), FASTA scores: opt: 317, E(): 1.9e-12, (31.0% identity in 297 aa overlap); Q9S1V2 PUTATIVE GLYCOSYL TRANSFERASE from Streptomyces coelicolor (407 aa), FASTA scores: opt: 264, E(): 4.1e-09, (27.2% identity in 342 aa overlap); P72650|CRTX|SLR1125 ZEAXANTHIN GLUCOSYL TRANSFERASE from Synechocystis sp. strain PCC 6803 (419 aa), FASTA scores: opt: 251, E(): 2.8e-08, (26.8% identity in 295 aa overlap); etc. Very similar to P95130|MTCY349.25 from Mycobacterium tuberculosis (449 aa), FASTA score: opt: 2215, E(): 3.3e-132, (77.25% identity in 422 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium bovis, a frameshift due to a single base insertion (*-g) leads to a shorter product with a different COOH part compared to its homolog in Mycobacterium tuberculosis strain H37Rv. |
Functional category | |
Mutant | Check for mutants available at TARGET website |
Coordinates
Type | Start | End | Orientation |
---|---|---|---|
CDS | 3267589 | 3268689 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2982c|Mb2982c MEETSVAGDPGPDAGTSTAPNAAPEPVARRQRILFVGEAATLAHVVRPFVLARSLDPSRYEVHFACDPRFNKLLGPLPFPHHPIHTVPSEEVLLKIAQGRLFYNTRTLRKYIAADRKILNEIAPDVVVGDNRLSLSVSARLAGIPYIAIANAYWSPQARRRFPLPDVPWTRFFGVRPVSILYRLYRPLIFALYCLPLNWLRRKHGLSSLGWDLCRIFTDGDYTLYADVPELVPTYNLPANHRYLGPVLWSPDVKPPTWWHSLPTDRPIIYATLGSSGGKNLLQVVLNALGRFTRDGDRGHRWPEPPEERAGQRLRRGLPAGRSGCSALRRGALQRRQPDDAAGVGGRGAGDRAPQQHGPALEHGGP
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