Gene Mb2986c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb2986c
Gene length1350 bp
IdentifierMb2986c
Location 3270462 bp
Protein summary information
Molecular mass49433.1 Da
Isoelectric point9.8772
Protein length449 amino acids
Orthologs
M. tuberculosis H37RvRv2962c
M. tuberculosis MTBC0mtbc0_003145
Cross-references
UniProtKB/TrEMBLX2BMC4, Q7TXJ4
SWISS-MODELQ7TXJ4
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE GLYCOSYL TRANSFERASE
CommentsMb2986c, -, len: 449 aa. Equivalent to Rv2962c,len: 449 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 449 aa overlap). Possible glycosyl transferase (EC 2.4.1.-), highly similar or identical to Mycobacterium tuberculosis proteins G560522 U0002JA,G560521 U0002H, G560522 U0002JA, G560519 U0002KA. Equivalent (but longer 21 aa) to Q9CD91 PUTATIVE GLYCOSYL TRANSFERASE from Mycobacterium leprae (438 aa), FASTA scores: opt: 2229, E(): 1.3e-133, (77.45% identity in 426 aa overlap); and highly similar to Q9CD88 PUTATIVE GLYCOSYL TRANSFERASE from Mycobacterium leprae (435 aa),FASTA scores: opt: 2129, E(): 2.7e-127, (74.35% identity in 425 aa overlap); and others from Mycobacterium leprae. Also shows some similarity to variety of glycosyl transferases e.g. Q9RYI3|DRA0329 PUTATIVE GLYCOSYL TRANSFERASE from Deinococcus radiodurans (418 aa), FASTA scores: opt: 340, E(): 5.5e-14, (31.2% identity in 330 aa overlap); P72650 ZEAXANTHIN GLUCOSYL TRANSFERASE from Synechocystis sp. (strain PCC 6803) (419 aa), FASTA scores: opt: 244, E(): 6.6e-08, (26.2% identity in 294 aa overlap); etc. Also highly similar to P95134 HYPOTHETICAL 46.8 KDA PROTEIN from Mycobacterium tuberculosis (428 aa),FASTA scores: opt: 2215, E(): 9.6e-133, (77.25% identity in 422 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32704623271811-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb2986c|Mb2986c
MRVSCVYATASRWGGPPVASEVRGDAAISTTPDAAPGLAARRRRILFVAEAVTLAHVVRPFALAQSLDPSRYEVHFACDPRYNQLLGPLPFRHHAIHTIPSERFFGNLTQGRFYAMRTLRKYVEADLRVLDEIAPDLVVGDLRISLSVSARLAGIPYIAIANAYWSPYAQRRFPLPDVIWTRLFGVRLVKLLYRLERPLLFALQCMPLNWVRRRHGLSSLGWNLCRIFTDGDHTLYADVPELMPTYDLPANHEYLGPVLWSPAGKPPTWWDSLPTDRPIVYATLGTSGGRNLLQLVLNALAELPVTVIAATAGRSDLKTVPANAFVADYLPGEAAAARSAVVVCNGGSLTTQQALVAGVPVIGVAGNLDQHLNMEAVERAGAGVLLRTERLKSQRVAGAVMQVISRSEYRQAAARLADAFGRDRVGFPQHVENALRLMPENRPRTWLAS
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