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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE HYDROLASE MUTT1
CommentsMb3009, mutT1, len: 317 aa. Equivalent to Rv2985,len: 317 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 317 aa overlap). Possible mutT1, long mutt protein (hydrolase) (EC 3.-.-.-), highly similar to O33126|MLCB637.35 HYPOTHETICAL 34.5 KDA PROTEIN from Mycobacterium leprae (312 aa), FASTA scores: opt: 1514,E(): 5.1e-91, (71.85% identity in 316 aa overlap); and Q9CBR8|ML1682 HYPOTHETICAL PROTEIN from Mycobacterium leprae (311 aa), FASTA scores: opt: 1510, E(): 9.2e-91,(71.5% identity in 316 aa overlap). Also similar to Q50195|L222-ORF6|ML2698 HYPOTHETICAL PROTEIN from Mycobacterium leprae (251 aa), FASTA scores: opt: 231,E(): 1.1e-07, (36.7% identity in 128 aa overlap). Also similar to shorter mutt proteins and related hypothetical protein e.g. Q9EUS6 HYPOTHETICAL 16.6 KDA PROTEIN from Streptomyces griseus subsp. griseus (152 aa), FASTA scores: opt: 380, E(): 1.7e-17, (50.75% identity in 130 aa overlap); Q9KZV8|SCD84.10C PUTATIVE MUTT-LIKE PROTEIN from Streptomyces coelicolor (142 aa), FASTA scores: opt: 376,E(): 2.9e-17, (46.1% identity in 128 aa overlap); P96590|MUTT MUTT PROTEIN from Bacillus subtilis (149 aa),FASTA scores: opt: 180, E(): 0.00017, (35.25% identity in 122 aa overlap); etc. Also similar to O05437 HYPOTHETICAL 27.1 KDA PROTEIN from Mycobacterium tuberculosis (248 aa),FASTA scores: opt: 224, E(): 3.2e-07, (34.03% identity in 144 aa overlap). Contains PS00893 mutT domain signature. SEEMS TO BELONG TO THE MUTT/NUDIX FAMILY PROTEIN.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32987253299678+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3009|mutT1
MSIQNSSARRRSAGRIVYAAGAVLWRPGSADSEGPVEIAVIHRPRYDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVTYPTDSPFRGVKKVHYWAARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQDRKVLCRFAKHPADTQTVLVVRHGTAGSKAHFSGDDSKRPLDKRGRAQAEALVPQLLAFGATDVYAADRVRCHQTMEPLAAELNVTIHNEPTLTEESYANNPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHPDKSRNRKGSTWVLSLSAGRLVTADHIGGALAANVRA
      
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