Gene Mb3009 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namemutT1
Gene length954 bp
IdentifierMb3009
Location 3298725 bp
Protein summary information
Molecular mass34780.4 Da
Isoelectric point9.5722
Protein length317 amino acids
Orthologs
M. tuberculosis H37RvRv2985
M. tuberculosis MTBC0mtbc0_003170
Cross-references
InterProIPR000086, IPR013078, IPR015797, IPR020084, IPR020476
UniProtKB/TrEMBLQ7TXH7
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE HYDROLASE MUTT1
CommentsMb3009, mutT1, len: 317 aa. Equivalent to Rv2985,len: 317 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 317 aa overlap). Possible mutT1, long mutt protein (hydrolase) (EC 3.-.-.-), highly similar to O33126|MLCB637.35 HYPOTHETICAL 34.5 KDA PROTEIN from Mycobacterium leprae (312 aa), FASTA scores: opt: 1514,E(): 5.1e-91, (71.85% identity in 316 aa overlap); and Q9CBR8|ML1682 HYPOTHETICAL PROTEIN from Mycobacterium leprae (311 aa), FASTA scores: opt: 1510, E(): 9.2e-91,(71.5% identity in 316 aa overlap). Also similar to Q50195|L222-ORF6|ML2698 HYPOTHETICAL PROTEIN from Mycobacterium leprae (251 aa), FASTA scores: opt: 231,E(): 1.1e-07, (36.7% identity in 128 aa overlap). Also similar to shorter mutt proteins and related hypothetical protein e.g. Q9EUS6 HYPOTHETICAL 16.6 KDA PROTEIN from Streptomyces griseus subsp. griseus (152 aa), FASTA scores: opt: 380, E(): 1.7e-17, (50.75% identity in 130 aa overlap); Q9KZV8|SCD84.10C PUTATIVE MUTT-LIKE PROTEIN from Streptomyces coelicolor (142 aa), FASTA scores: opt: 376,E(): 2.9e-17, (46.1% identity in 128 aa overlap); P96590|MUTT MUTT PROTEIN from Bacillus subtilis (149 aa),FASTA scores: opt: 180, E(): 0.00017, (35.25% identity in 122 aa overlap); etc. Also similar to O05437 HYPOTHETICAL 27.1 KDA PROTEIN from Mycobacterium tuberculosis (248 aa),FASTA scores: opt: 224, E(): 3.2e-07, (34.03% identity in 144 aa overlap). Contains PS00893 mutT domain signature. SEEMS TO BELONG TO THE MUTT/NUDIX FAMILY PROTEIN.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS32987253299678+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3009|mutT1
MSIQNSSARRRSAGRIVYAAGAVLWRPGSADSEGPVEIAVIHRPRYDDWSLPKGKVDPGETAPVGAVREILEETGHRANLGRRLLTVTYPTDSPFRGVKKVHYWAARSTGGEFTPGSEVDELIWLPVPDAMNKLDYAQDRKVLCRFAKHPADTQTVLVVRHGTAGSKAHFSGDDSKRPLDKRGRAQAEALVPQLLAFGATDVYAADRVRCHQTMEPLAAELNVTIHNEPTLTEESYANNPKRGRHRVLQIVEQVGTPVICTQGKVIPDLITWWCERDGVHPDKSRNRKGSTWVLSLSAGRLVTADHIGGALAANVRA
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