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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ALANINE RICH DEHYDROGENASE
CommentsMb3021, -, len: 480 aa. Equivalent to Rv2997, len: 480 aa, from Mycobacterium tuberculosis strain H37Rv,(99.8% identity in 480 aa overlap). Possible ala-rich dehydrogenase (EC 1.-.-.-), similar to others dehydrogenases and hypothetical proteins e.g. Q9EYI5 PUTATIVE DEHYDROGENASE from Streptomyces nogalater (472 aa), FASTA scores: opt: 1131, E(): 1.7e-61, (41.0% identity in 471 aa overlap); Q9ZBG4|SC9B5.16 PUTATIVE DEHYDROGENASE from Streptomyces coelicolor (472 aa), FASTA scores: opt: 1064, E(): 2e-57, (39.05% identity in 471 aa overlap); Q98BS8 PROBABLE DEHYDROGENASE from Rhizobium loti (Mesorhizobium loti) (524 aa), FASTA scores: opt: 196, E(): 0.00021, (25.1% identity in 526 aa overlap); etc. Shows strong simlarity throughout its length to O06826|MTCY493.22c|Rv1432 HYPOTHETICAL 50.5 KDA PROTEIN from Mycobacterium tuberculosis (473 aa), FASTA scores: opt: 1220, E(): 6.1e-67, (42.35% identity in 465 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33117153313157+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3021|Mb3021
MDVTVVGSGPNGLATAVICARAGLNVQVVEAQATFGGGARSAADFEFPEVLHDVCSAVHPLALASPFFAEFDLPARGVTLTVPDIAYANPLPGRPAAIAYHDLAHTSAKLDDGASWRRLLGPLVAHSETVVEFMLSDKRSLPTALGSVLRLGLRMLAQGTPAWRSLAGEDARALFTGVAAHAISPLPSLVSAGAGLMLATLAHSVGWPIPVGGTQAIADALIADLRAHGGRLAAGVEITEPQRSVVVFDTAPTALLRVYRDKLPHRYAKALRRYRFRAGIAKVDFVLSDEIPWSDPRLRRAATLHLGGTRDQMARAEADVAAGRHADWPMVLAACPHVADPGRIDETGRRPFWTYAHVPSGSTLDATETVTSVLERFAPGFRDIVVAARAVPAARMADHNANYVGGDITVGANSTWRAIAGPTPRLNPWRTPIPKVYLCSAATPPGAGVHGMCGWYAARTLLRTEFGITRMPPLGHELRP
      
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