Gene Mb3034c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegatB
Gene length1530 bp
IdentifierMb3034c
Location 3323879 bp
Protein summary information
Molecular mass54632.9 Da
Isoelectric point4.8452
Protein length509 amino acids
Orthologs
M. tuberculosis H37RvRv3009c
M. tuberculosis MTBC0mtbc0_003198
Cross-references
UniProtKB/TrEMBLX2BM48, P64200
SWISS-MODELP64200
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT B) GATB (Glu-ADT SUBUNIT B)
CommentsMb3034c, gatB, len: 509 aa. Equivalent to Rv3009c,len: 509 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 509 aa overlap). Probable gatB,Glu-tRNA-Gln amidotransferase, subunit B (EC 6.3.5.-),equivalent to O33107|GATB_MYCLE|MLCB637_15 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium leprae (509 aa), FASTA scores: opt: 2973, E(): 2.9e-173,(88.4% identity in 509 aa overlap). Also highly similar to other Glu- tRNA-Gln amidotransferases e.g. Q9Z578|GATB|SC8D9.13 from Streptomyces coelicolor (504 aa), FASTA scores: opt: 2264, E(): 3.6e-130, (66.0% identity in 495 aa overlap); P74215|GATB_SYNY3|SLL1435 from Synechocystis sp. strain PCC 6803 (519 aa), FASTA scores: opt: 1289, E(): 6.7e-71, (42.0% identity in 485 aa overlap); Q9X100|GATB_THEMA|TM1273 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Thermotoga maritima (482 aa), FASTA scores: opt: 1165, E(): 2.2e-63, (40.05% identity in 487 aa overlap); etc. For more information about function, see citation below. Similar to many members of the pet112 family. BELONGS TO THE GATB FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33238793325408-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3034c|gatB
MTVAAGAAKAAGAELLDYDEVVARFQPVLGLEVHVELSTATKMFCGCTTTFGGEPNTQVCPVCLGLPGSLPVLNRAAVESAIRIGLALNCEIVPWCRFARKNYFYPDMPKNYQISQYDEPIAINGYLDAPLEDGTTWRVEIERAHMEEDTGKLTHIGSETGRIHGATGSLIDYNRAGVPLIEIVTKPIVGAGARAPQIARSYVTALRDLLRALDVSDVRMDQGSMRCDANVSLKPAGTTEFGTRTETKNVNSLKSVEVAVRYEMQRQGAILASGGRITQETRHFHEAGYTSAGRTKETAEDYRYFPEPDLEPVAPSRELVERLRQTIPELPWLSRRRIQQEWGVSDEVMRDLVNAGAVELVAATVEHGASSEAARAWWGNFLAQKANEAGIGLDELAITPAQVAAVVALVDEGKLSNSLARQVVEGVLAGEGEPEQVMTARGLALVRDDSLTQAAVDEALAANPDVADKIRGGKVAAAGAIVGAVMKATRGQADAARVRELVLEACGQG
Bibliography
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