Gene Mb3036c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namegatA
Gene length1485 bp
IdentifierMb3036c
Location 3326565 bp
Protein summary information
Molecular mass51436.2 Da
Isoelectric point4.6972
Protein length494 amino acids
Orthologs
M. tuberculosis H37RvRv3011c
M. tuberculosis MTBC0mtbc0_003200
Cross-references
UniProtKB/TrEMBLX2BMB5, Q7TXG2
SWISS-MODELQ7TXG2
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE (SUBUNIT A) GATA (Glu-ADT SUBUNIT A)
CommentsMb3036c, gatA, len: 494 aa. Equivalent to Rv3011c,len: 494 aa, from Mycobacterium tuberculosis strain H37Rv,(99.4% identity in 494 aa overlap). Probable gatA,Glu-tRNA-Gln amidotransferase, subunit A (EC 6.3.5.-),equivalent to O33105|GATA|ML1702|MLCB637.13 GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Mycobacterium leprae (497 aa), FASTA scores: opt: 2839, E(): 3.5e-161,(88.8% identity in 492 aa overlap). Also highly similar to other Glu-tRNA-Gln amidotransferases e.g. Q9Z580|GATA_STRCO from Streptomyces coelicolor (497 aa),FASTA scores: opt: 2231, E(): 4.5e-125, (70.3% identity in 486 aa overlap); P73558|GATA_SYNY3|SLR0877 from Synechocystis sp. strain PCC 6803 (483 aa), FASTA scores: opt: 1593, E(): 3.3e-87, (55.85% identity in 487 aa overlap); O06491|GATA_BACSU GLUTAMYL-TRNA(GLN) AMIDOTRANSFERASE from Bacillus subtilis (485 aa), FASTA scores: opt: 1389, E(): 4.3e-75, (51.7% identity in 468 aa overlap); etc. For more information about function, see citation below. Contains PS00017 ATP/GTP-binding site motif A (P-loop). BELONGS TO THE AMIDASE FAMILY.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33265653328049-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3036c|gatA
MTDIIRSDAATLAAKIAIKEVSSTEITRACLDQIEATDETYHAFLHVAADEALAAAAAVDKQVAAGEPLPSALAGVPLALKDVFTTSDMPTTCGSKILEGWRSPYDATLTARLRAAGIPILGKTNMDEFAMGSSTENSAYGPTRNPWNLDRVPGGSGGGSAAALAAFQAPLAIGSDTGGSIRQPAALTATVGVKPTYGTVSRYGLVACASSLDQGGPCARTVLDTALLHQVIAGHDPRDSTSVDAEVPDVVGAARAGAVGDLRGVRVGVVRQLHGGEGYQPGVLASFEAAVEQLTALGAEVSEVDCPHFDHALAAYYLILPSEVSSNLARFDAMRYGLRVGDDGTRSAEEVMAMTRAAGFGPEVKRRIMIGTYALSAGYYDAYYNQAQKVRTLIARDLDAAYRSVDVLVSPTTPTTAFRLGEKVDDPLAMYLFDLCTLPLNLAGHCGMSVPSGLSPDDGLPVGLQIMAPALADDRLYRVGAAYEAARGPLLSAI
Bibliography
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