Gene Mb3046c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameesxS
Gene length294 bp
IdentifierMb3046c
Location 3335595 bp
Protein summary information
Molecular mass9842.03 Da
Isoelectric point6.6764
Protein length97 amino acids
Orthologs
M. tuberculosis H37RvRv3020c
M. tuberculosis MTBC0mtbc0_003211
Cross-references
InterProIPR010310
UniProtKB/TrEMBLQ7TXF7
SWISS-MODELA0A1R3Y2X0
General annotation
TypeCDS
FunctionUnknown
Productesat-6 like protein esxs
CommentsMb3046c, esxS, len: 97 aa. Equivalent to Rv3020c,len: 97 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 97 aa overlap). Member of Mycobacterium tuberculosis PE family (see first citation below), similar to others e.g. AAK44524|MT0300 PE FAMILY PROTEIN from M. tuberculosis strain CDC1551 (97 aa), FASTA scores: opt: 564, E(): 5.9e-30, (91.75% identity in 97 aa overlap). Has potential helix-turn-helix motif at positions 14-35. TBparse score is 0.912. SEEMS TO BELONG TO THE ESAT6 FAMILY (see second citation below).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33355953335888-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3046c|esxS
MSLLDAHIPQLIASHTAFAAKAGLMRHTIGQAEQQAMSAQAFHQGESAAAFQGAHARFVAAAAKVNTLLDIAQANLGEAAGTYVAADAAAASSYTGF
Bibliography
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