Gene Mb3047c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ppe family protein ppe47 |
| Comments | Mb3047c, PPE47, len: 435 aa. Equivalent to Rv3022c (PPE48) and Rv3021c (PPE47), len: 81 aa and 358 aa, from Mycobacterium tuberculosis strain H37Rv, (98.8% identity in 81 aa overlap and 98.6% identity in 354 aa overlap). Member of Mycobacterium tuberculosis PPE family. Should be continuation of upstream ORF MTV012.36c but is frameshifted due to missing base at 36448 in v012. Sequence has been checked but no error apparent. Very similar to neighbouring ORF O53265|MTV012.32c|Rv3018c from Mycobacterium tuberculosis (434 aa), FASTA scores: opt: 1714, E(): 6.6e-770, (78.3% identity in 355 aa overlap) and AAK47430|MT3101 (strongly in the N-terminal part) (310 aa), FASTA scores: opt: 897, E(): 4.5e-37, (66.95% identity in 227 aa overlap). REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis H37Rv, PPE47 and PPE48 exist as 2 separate genes. In Mycobacterium bovis, a single base insertion (*-g) leads to a single product. |
| Functional category | Pe/ppe |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3335935 | 3337242 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3047c|PPE47
MTAPVWLASPPEVHSALLSAGPGPGSLQAAAAGWSALSAEYAAVAQELSAVVAAVGAGVWQGPSAELFVAAYVPYVAWLVQASADSAAAAGEHEAAAAGYVCALAEMPTLPELAANHLTHAVLVATNFFGINTIPIALNEADYVRMWVQAATVMSAYEAVVGAALVATPHTGPAPVIVKPGANEASNAVAAATITPFPFGELAKFLEMAAQAFTEVGELIMKSAEAWAVGFVELITGLVNFEPWLVLTGMIDMFFATVGFALGVFVLVPLLEFAVVLELAILSIGWIISNIFGAIPVLAGPLLGALAAAVVPGVAGVTGLAGLAAVPAVGAAAGAPAALVGSVAPVSGGVVSPQARLVSAVEPAPASTSVSVLASDRGAGALGFVGTAGKESVGQPAGLTVLADEFGDGAPVPMLPGSWGPDLVGVAGDGGLVSV
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