Gene Mb3083c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene nameMb3083c
Gene length864 bp
IdentifierMb3083c
Location 3374345 bp
Protein summary information
Molecular mass31153.8 Da
Isoelectric point9.9703
Protein length287 amino acids
Orthologs
M. tuberculosis H37RvRv3057c
M. tuberculosis MTBC0mtbc0_003249
Cross-references
InterProIPR002198, IPR002347, IPR016040, IPR020904
UniProtKB/TrEMBLQ7TXC8
SWISS-MODELA0A1R3Y3D4
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE SHORT CHAIN ALCOHOL DEHYDROGENASE/REDUCTASE
CommentsMb3083c, -, len: 287 aa. Equivalent to Rv3057c,len: 287 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 287 aa overlap). Probable oxidoreductase, probably short-chain alcohol dehydrogenase/reductase (EC 1.1.-.-). Equivalent to Q9CBP7|ML1740 POSSIBLE SHORT CHAIN DEHYDROGENASES/REDUCTASE from Mycobacterium leprae (312 aa), FASTA scores: opt: 1563, E(): 6e-89, (81.8% identity in 280 aa overlap). Also similar to many oxidoreductases e.g. Q9ZBX8|SCD78.21c PUTATIVE OXIDOREDUCTASE from Streptomyces coelicolor (585 aa), FASTA scores: opt: 541,E(): 6.7e-26, (37.25% identity in 263 aa overlap); AAK47506|MT3170 OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY from Mycobacterium tuberculosis strain CDC1551 (276 aa), FASTA scores: opt: 521, E(): 6.1e-25, (36.25% identity in 276 aa overlap); AAK45541|MT1283 OXIDOREDUCTASE, SHORT-CHAIN DEHYDROGENASE/REDUCTASE FAMILY from Mycobacterium tuberculosis strain CDC1551 (276 aa), FASTA scores: opt: 471, E(): 7.2e-22, (32.4% identity in 281 aa overlap). Also similar to O50460|Rv1245c|MTV006.17C DEHYDROGENASE (276 aa). Contains short-chain alcohol dehydrogenase family signature (PS00061). MAY BELONG TO THE SHORT-CHAIN DEHYDROGENASES/REDUCTASES (SDR) FAMILY.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS33743453375208-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3083c|Mb3083c
MLQRGAGQYFAGKRCFVTGAASGIGRATALRLAAQGAELYLTDRDRDGLAQTVCDARALGAQVPEHRVLDVSDYQDVAAFAADIHARHPSMDVVLNIAGVSAWGTVDQLTHDQWSRMVAINLMGPIHVIETLVPPMVAAGRGGHLVNVSSAAGLVGLPWHAAYSASKYGLRGLSEVLRFDLARHGIGVSVVVPGAVKTPLVNTVEIAGVDRDDPRVNRWVERFSGHAVTPEKAADKILAGVTRNRYLVYTSADIRALYAFKRYAWWPYTLVMRRVNVFFTRALRPGP
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