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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE AGPS (ALKYL-DHAP SYNTHASE) (ALKYLGLYCERONE-PHOSPHATE SYNTHASE)
CommentsMb3134c, agpS, len: 527 aa. Equivalent to Rv3107c,len: 527 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 527 aa overlap). Possible agpS,alkyl-dihydroxyacetonephosphate synthase (EC 2.5.1.26),similar to others and some various enzymes e.g. AAK46595|MT2311 PUTATIVE ALKYL-DIHYDROXYACETONEPHOSPHATE SYNTHASE from Mycobacterium tuberculosis strain CDC1551 (529 aa), FASTA scores: opt: 1052, E(): 2.1e-58, (37.1% identity in 542 aa overlap); Q9RJ97|SCF91.28c PUTATIVE FLAVOPROTEIN from Streptomyces coelicolor (530 aa), FASTA scores: opt: 972, E(): 2.2e-53, (36.2% identity in 544 aa overlap); O96759|ADAS_DICDI ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE (EC 2.5.1.26) from Dictyostelium discoideum (Slime mold) (611 aa), FASTA scores: opt: 617, E(): 4.5e-31, (33.95% identity in 480 aa overlap); O97157|ADAS_TRYBB ALKYLDIHYDROXYACETONEPHOSPHATE SYNTHASE from Trypanosoma brucei (613 aa), FASTA scores: opt: 567,E(): 6.2e-28, (29.15% identity in 521 aa overlap); etc. Also similar to O53525|Rv2251|MTV022.01 HYPOTHETICAL 49.8 KDA PROTEIN from Mycobacterium tuberculosis strain H37Rv (475 aa), FASTA scores: opt: 1019, E(): 2.3e-56, (38.6% identity in 487 aa overlap). BELONGS TO THE FAD-BINDING OXIDOREDUCTASE/TRANSFERASE FAMILY 4. COFACTOR: FAD (BY SIMILARITY).
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34319263433509-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3134c|agpS
MRSWWGWGTVEDALSDQETQALQSRVAALVSGHDLSDHPPPDLTALGLAAPRVSPPASLAALCSSDLVDRAGHARGKAYRDIARNLQGQLDHLPDLIARPRSEQDVIDVLDWCAREGIAVIPYGGGSSVVGGVEPRFDEPVVTVDVTAMSAVLEIDRVSRAARIQAGAFGPSIEHQLRPHDLTLRHFPQSFGFSTLGGWLATRSGGHFATLYTHIDDLTESLRIVTPVGISESRRLPGSGAGPSPDRLFLGSEGTLGIITEAWMRLQHRPRWQVTVSVVFDDWAAAVAATRTIAQAGLYPANCRLLDPAEALLNAGTSVGGGLLVLAFESADHPIDPWLHRAVAITAEHGGTVTAQRSRGTTSDATEHNAAANWRSAFLRMPYQRDALVRRGVIAETFETACTWDGFDTLHAAVTDAARTAIWKVCGTGVVTCRFTHVYPDGPAPYYGIYAGGRWGSLDAQWDEIKAAVSEAISASGGTITHHHAVGRDHRAWYDRQRPDPFAAALRAAKSALDPAGILNPGVLLGR
      
Bibliography
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