Gene Mb3185c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| Comments | Mb3185c, -, len: 213 aa. Equivalent to Rv3160c,len: 213 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 213 aa overlap). Possible transcriptional regulator, with some similarity to others e.g. Q9S3L4|AMTR AMTR PROTEIN (global repressor in the nitrogen regulation system; see first citation below for more information) (222 aa), FASTA scores: opt: 182, E(): 7.3e-05, (27.9% identity in 208 aa overlap); Q9X7X9|SC6A5.33c PUTATIVE REGULATORY PROTEIN from Streptomyces coelicolor (223 aa), FASTA scores: opt: 176,E(): 0.00018, (26.5% identity in 185 aa overlap); Q9XA31|SCH69.03c PUTATIVE TRANSCRIPTIONAL REGULATOR from Streptomyces coelicolor (209 aa), FASTA scores: opt: 173,E(): 0.00027, (27.25% identity in 176 aa overlap); BAB54133|MLL7734 TRANSCRIPTIONAL REGULATOR from Rhizobium loti (Mesorhizobium loti) (213 aa), FASTA scores: opt: 172, E(): 0.00031, (23.55% identity in 204 aa overlap); etc. Also similar to hypothetical proteins from Mycobacterium tuberculosis strain H37Rv e.g. P96839|Rv3557v|MTCY06G11.04c (200 aa), FASTA scores: opt: 169, E(): 0.00046, (26.75% identity in 157 aa overlap). Contains probable helix-turn-helix motif from aa 31 to 52 (Score 1857, +5.51 SD). SIMILAR TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS. TBparse score is 0.901. |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3486590 | 3487231 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3185c|Mb3185c
MPRQAGRWSPTALRILGAAAELIALRGYSSTSTRDIAAAVGVEQPAIYKHFSAKRDILAALVRLAVEWPLELFGHITAMPVPAVVKLHRWLTESLDHLHASPYVLVSILITPDLHQESFVAERELVAEMERALVGLIETGQGEGDVRAMHPLSAARLVQALFDALALPEFAVSPDEIVEFAMTALLSDPDRLAEIRAAADALEIQTAPPDRGL
Bibliography
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