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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
CommentsMb3192c, -, len: 208 aa. Equivalent to Rv3167c,len: 208 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 208 aa overlap). Probable transcriptional regulator, tetR family, similar to several transcriptional regulators e.g. Q9L2A4|SC8F4.22c (TETR/ACRR FAMILY) from Streptomyces coelicolor (234 aa),FASTA scores: opt: 317, E(): 7.5e-13, (33.35% identity in 210 aa overlap); Q9RK47|SCF12.11 (TETR/ACRR FAMILY) from Streptomyces coelicolor (206 aa), FASTA scores: opt: 293,E(): 2.1e-11, (32.65% identity in 199 aa overlap); Q54288 REGULATOR OF ANTIBIOTIC TRANSPORT COMPLEXES (TETR/ACRR FAMILY) (204 aa), FASTA scores: opt: 260, E(): 2.4e-09,(30.75% identity in 205 aa overlap); etc. Equivalent to AAK47595 from Mycobacterium tuberculosis strain CDC1551 but shorter 21 aa. Contains probable helix-turn-helix motif from aa 42 to 63 (Score 1727, +5.07 SD). MAY BE BELONG TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS.
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS34926823493308-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3192c|Mb3192c
MKADLPSLDKAPGAGRPRDPRIDSAILSATAELLVQIGYSNLSLAAVAERAGTTKSALYRRWSSKAELVHEAAFPAAPTALQAAAGDIAADIRMMIAATRDVFTTPVVRAALPGLVADMTADAELNARVLARFADLFAAVRMRLREAVDRGEAHPDVDPDRLIELIGGATMLRMLLYPDDMLDDAWVDQTTAIVVRGVHRAAPGGSVV
      
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