Gene Mb3228 in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelipV
Gene length786 bp
IdentifierMb3228
Location 3535071 bp
Protein summary information
Molecular mass27868.0 Da
Isoelectric point5.7163
Protein length261 amino acids
Orthologs
M. tuberculosis H37RvRv3203
M. tuberculosis MTBC0mtbc0_003408
Cross-references
UniProtKB/TrEMBLX2BNB5
SWISS-MODELA0A1R3Y3L7
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE LIPASE LIPV
CommentsMb3228, lipV, len: 261 aa. Equivalent to alpha/beta hydrolase from Mycobacterium tuberculosis strain CDC1551 (100% identity with 260 aa overlap). Similar to Rv3203,len: 224 aa, from Mycobacterium tuberculosis strain H37Rv,(86.0% identity in 224 aa overlap). Possible lipV,hydrolase lipase (EC 3.1.-.-), showing some similarity to other lipases e.g. Q9JSN0|NMA2216 PUTATIVE HYDROLASE from Neisseria meningitidis (serogroup A) (312 aa),Q9RK95|SCF1.09 PUTATIVE HYDROLASE from Streptomyces coelicolor (258 aa), Q9KZC3|SC6F7.19c PUTATIVE LIPASE from Streptomyces coelicolor (269 aa), etc. Contains serine active site signature of lipases (PS00120). Mb3228 transcript and transcriptional start site identified in Mycobacterium bovis strain AF2122/97 grown under exponential conditions.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35350713535856+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3228|lipV
MIIDLHVQRYGPSGPARVLTIHGVTEHGRIWHRLAHHLPEIPIAAPDLLGHGRSPWAAPWTIDANVSALAALLDNQGDGPVVVVGHSFGGAVAMHLAAARPDQVAALVLLDPAVALDGSRVREVVDAMLASPDYLDPAEARAEKATGAWADVDPPVLDAELDEHLVALPNGRYGWRISLPAMVCYWSELARDIVLPPVGTATTLVRAVRASPAYVSDQLLAALDKRLGADFELLDFDCGHMVPQAKPTEVAAVIRSRLGPR
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