Gene Mb3241
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE ISOCHORISMATE SYNTHASE ENTC (ISOCHORISMATE HYDROXYMUTASE) (ENTEROCHELIN BIOSYNTHESIS) |
| Comments | Mb3241, entC, len: 372 aa. Equivalent to Rv3215,len: 372 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 372 aa overlap). Probable entC,isochorismate synthase (EC 5.4.99.6), equivalent to Q9CCH5|ENTC|ML0808 PUTATIVE ISOCHORISMATE SYNTHASE from Mycobacterium leprae (577 aa), FASTA scores: opt: 1817,E(): 5.5e-105, (73.5% identity in 366 aa overlap). Also similar to others e.g. Q9F639|MXCD PROTEIN INVOLVED IN MYXOCHELIN-TYPE IRON CHELATOR BIOSYNTHESIS (see citation below) from Stigmatella aurantiaca (408 aa), FASTA scores: opt: 893, E(): 6.2e-48, (41.6% identity in 382 aa overlap); P45744|DHBC_BACSU ISOCHORISMATE SYNTHASE from Bacillus subtilis (398 aa), FASTA scores: opt: 883, E(): 2.5e-47, (40.45% identity in 393 aa overlap); Q9KI93|CSBC ISOCHORISMATE SYNTHASE (FRAGMENT) from Azotobacter vinelandii (361 aa), FASTA scores: opt: 794, E(): 7.6e-42,(45.65% identity in 298 aa overlap); and the two Escherichia coli proteins AAG54928|ENTC (alias BAB34055|ECS0632) ISOCHORISMATE HYDROXYMUTASE 2 from Escherichia coli strain O157:H7 (391 aa), FASTA scores: opt: 744, E(): 1e-38, (38.8% identity in 340 aa overlap); P10377|ENTC|B0593 ISOCHORISMATE SYNTHASE from Escherichia coli strain K12 (391 aa), FASTA scores: opt: 744, E(): 1e-38, (38.8% identity in 340 aa overlap); etc. Stronger similarity to Escherichia coli entC. Also similar to MTCY253.35. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3546797 | 3547915 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3241|entC
MSAHVATLHPEPPFALCGPRGTLIARGVRTRYCDVRAAQAALRSGTAPILLGALPFDVSRPAALMVPDGVLRARKLPDWPTGPLPKVRVAAALPPPADYLTRIGRARDLLAAFDGPLHKVVLARAVQLTADAPLDARVLLRRLVVADPTAYGYLVDLTSAGNDDTGAALVGASPELLVARSGNRVMCKPFAGSAPRAADPKLDAANAAALASSAKNRHEHQLVVDTMRVALEPLCEDLTIPAQPQLNRTAAVWHLCTAITGRLRNISTTAIDLALALHPTPAVGGVPTKAATELIAELEGDRGFYAGAVGWCDGRGDGHWVVSIRCAQLSADRRAALAHAGGGIVAESDPDDELEETTTKFATILTALGVEQ
Bibliography
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