Gene Mb3262c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | possible triacylglycerol synthase (diacylglycerol acyltransferase) |
| Comments | Mb3262c, -, len: 469 aa. Equivalent to Rv3234c and Rv3233c, len: 271 aa and 196 aa, from Mycobacterium tuberculosis strain H37Rv, (100.0% identity in 266 aa overlap and 100.0% identity in 196 aa overlap). Rv3234c: Hypothetical protein, similar to C-terminus of Mycobacterium tuberculosis hypothetical proteins e.g. P71694|Rv1425|MTCY21B4.43|MTCY493.29c (459 aa), FASTA scores: opt: 498, E(): 5.2e-24, (36.8% identity in 261 aa overlap); MTCY03A2.28; MTCY31.23; MTCY493_29; MTCY28_26; MTV013_8; MTY13E12_33; etc. Also similar to Q9X7A8|MLCB1610.05|ML1244 CONSERVED MEMBRANE PROTEIN from Mycobacterium leprae (491 aa), FASTA scores: opt: 309,E(): 4.3e-12, (33.35% identity in 189 aa overlap). Rv3233c: Hypothetical protein, similar to C-terminus of Q9RIU8|SCM11.13c HYPOTHETICAL 47.1 KDA PROTEIN from Streptomyces coelicolor (446 aa), FASTA scores: opt: 308,E(): 1.2e-12, (32.0% identity in 200 aa overlap); and several hypothetical Mycobacterium tuberculosis proteins e.g. O06343|YY80_MYCTU|Rv3480c|MTCY13E12.33c (497 aa),FASTA scores: opt: 248, E(): 9.8e-09, (27.5% identity in 200 aa overlap); MTCY28_26; MTCY493_29; MTCY31_25; MTCY31_25. REMARK-M.bovis-M.tuberculosis: In Mycobacterium tuberculosis H37Rv, Rv3234c and Rv3233c exist as 2 genes. In Mycobacterium bovis, a single base insertion (*-g) leads to a single product that is more similar to Rv3234c. |
| Functional category | Lipid metabolism |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3564380 | 3565789 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3262c|tgs3
MVTRLSASDASFYQLENTATPMYVGLLLILRRPRAGLSYEALLETVEQRLPQIPRYRQKVQEVKLGLARPVWIDDRDFDITYHVRRSALPSPGSDEQLHELIARLAARPLDKSRPLWEMYLVEGLEKNRIALYTKSHQALINGVTALAIGHVIADRTRRPPAFPEDIWVPERDPGTTRLLLRAVGDWLVRPGAQLQAVGSAVAGLVTNSGQLVETGRKVLDIARTVARGTAPSSPLNATVSRNRRFTVARASLDDYRTVRARYDCDVHDVVLTVIAGALGNWLMSRGEAVAPTATVRAMAPLSVYADDQLDSTGPGQAISQVTPFLVDLPVGEGNAVVRLSQIAHATESNPTAASLVDARTIVTLSGLAPATLHAMGVRVATSFSARLFNLLITNAPGTQSQMYIAGTKLLETYSVPPLLHNQALAISVTSYNGMLYFGINADRDAMSDVDLLPGLLSQALDELLEASR
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