Gene Mb3277c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | POSSIBLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY) |
| Comments | Mb3277c, -, len: 211 aa. Equivalent to Rv3249c,len: 211 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 211 aa overlap). Possible transcriptional regulatory protein, tetR family, with similarity to several e.g. Q9AE61|ALKB1 PUTATIVE TETR-REGULATORY from Rhodococcus erythropolis (208 aa),FASTA scores: opt: 503, E(): 7.7e-26, (40.6% identity in 192 aa overlap); CAC37620 PUTATIVE TETR-REGULATORY PROTEIN from Prauserella rugosa (212 aa), FASTA scores: opt: 246,E(): 4.4e-09, (27.95% identity in 186 aa overlap); Q9K4B0|SC7E4.06 PUTATIVE TETR-FAMILY TRANSCRIPTIONAL from Streptomyces coelicolor (203 aa), FASTA scores: opt: 224,E(): 1.1e-07, (34.5% identity in 197 aa overlap); Q11063|YC55_MYCTU|Rv1255c|MT1294|MTCY50.27 HYPOTHETICAL TRANSCRIPTIONAL REGULATOR from Mycobacterium tuberculosis (202 aa), FASTA scores: opt: 191, E(): 1.6e-05, (28.35% identity in 180 aa overlap); etc. Equivalent to AAK47689 from Mycobacterium tuberculosis strain CDC1551 (230 aa) but shorter 19 aa. COULD BELONG TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS. Possible helix-turn helix motif at aa 44-65 (+6.66 SD). |
| Functional category | Regulatory proteins |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3584352 | 3584987 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3277c|Mb3277c
MSTPSATVAPVKRIPYAEASRALLRDSVLDAMRDLLLTRDWSAITLSDVARAAGISRQTIYNEFGSRQGLAQGYALRLADRLVDNVHASLDANVGNFYEAFLQGFRSFFAESAADPLVISLLTGVAKPDLLQLITTDSAPIITRASARLAPAFTDTWVATTDNDANVLSRAIVRLCLSYVSMPPEADHDVAADLARLITPFAERHGVINVP
Bibliography
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