Gene Mb3288c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN WHIB-LIKE WHIB2 |
| Comments | Mb3288c, whiB2, len: 89 aa. Equivalent to Rv3260c,len: 89 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 89 aa overlap). Probable whiB2,WhiB-like regulatory protein (see first citation below),similar to WhiB paralogue of Streptomyces coelicolor, wblE gene product (85 aa). Equivalent to Q9CCK0|WHIB2|ML0760 PUTATIVE TRANSCRIPTIONAL REGULATOR from Mycobacterium leprae (89 aa), FASTA scores: opt: 550, E(): 6.1e-31,(85.4% identity in 89 aa overlap). Also similar to others e.g. Q9S426 WHMD REGULATORY PROTEIN (see second citation below) from Mycobacterium smegmatis (129 aa), FASTA scores: opt: 488, E(): 1.4e-26, (83.55% identity in 85 aa overlap); Q06387|WHIB-STV WHIB-STV PROTEIN from Streptomyces griseocarneus (87 aa), FASTA scores: opt: 443, E(): 1.2e-23, (74.7% identity in 83 aa overlap); Q05429|WHIB|WHIB1 TRANSCRIPTION-LIKE FACTOR WHIB from Streptomyces aureofaciens (87 aa), FASTA scores: opt: 442,E(): 1.3e-23, (74.7% identity in 83 aa overlap); etc. Equivalent to AAK47700 WhiB-related protein from Mycobacterium tuberculosis strain CDC1551 (123 aa) but shorter 34 aa. Also similar to other Mycobacterium tuberculosis proteins: MTCY07D11.07c (45.1% identity in 71 aa overlap) and MTCY78.13c (37.4% identity in 91 aa overlap). Start chosen by homology but ORF continues to ATG upstream at 3754. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3594472 | 3594741 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3288c|whiB2
MVPEAPAPFEEPLPPEATDQWQDRALCAQTDPEAFFPEKGGSTREAKKICMGCEVRHECLEYALAHDERFGIWGGLSERERRRLKRGII
Bibliography
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