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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE F420 BIOSYNTHESIS PROTEIN FBIA
CommentsMb3289, fbiA, len: 331 aa. Equivalent to Rv3261,len: 331 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 331 aa overlap). Probable fbiA, F420 biosynthesis protein, equivalent to FBIA F420 biosynthesis protein fbiA from Mycobacterium bovis BCG (see citations below). Also equivalent, but shorter 46 aa, to Q9CCK1|ML0759 HYPOTHETICAL PROTEIN from Mycobacterium leprae (379 aa), FASTA scores: opt: 1855, E(): 3.9e-110,(79.3% identity in 333 aa overlap). Also similar to others e.g. Q9KZK9|SCE34.17 HYPOTHETICAL 33.6 KDA PROTEIN from Streptomyces coelicolor (319 aa), FASTA scores: opt: 1151,E(): 1.2e-65, (55.1% identity in 332 aa overlap); O29345|AF0917 CONSERVED HYPOTHETICAL PROTEIN from Archaeoglobus fulgidus (296 aa), FASTA scores: opt: 469,E(): 1.7e-22, (31.15% identity in 302 aa overlap); Q58653|MJ1256 HYPOTHETICAL PROTEIN from Methanococcus jannaschii (311 aa), FASTA scores: opt: 436, E(): 2.2e-20,(27.35% identity in 274 aa overlap); etc.
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS35951433596138+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3289|fbiA
MKVTVLAGGVGGARFLLGVQQLLGLGQFAANSAHSDADHQLSAVVNVGDDAWIHGLRVCPDLDTCMYTLGGGVDPQRGWGQRDETWHAMQELVRYGVQPDWFELGDRDLATHLVRTQMLQAGYPLSQITEALCDRWQPGARLLPATDDRCETHVVITDPVDESRKAIHFQEWWVRYRAQVPTHSFAFVGAEKSSAATEAIAALADADIIMLAPSNPVVSIGAILAVPGIRAALREATAPIVGYSPIIGEKPLRGMADTCLSVIGVDSTAAAVGRHYGARCATGILDCWLVHDGDHAEIDGVTVRSVPLLMTDPNATAEMVRAGCDLAGVVA
      
Bibliography
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