Gene Mb3315c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | ANTI-SIGMA FACTOR RSBW (SIGMA NEGATIVE EFFECTOR) |
| Comments | Mb3315c, rsbW, len: 145 aa. Equivalent to Rv3287c,len: 145 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 145 aa overlap). rsbW (alternate gene name: usfX), anti-sigma factor (see citations below),similar to Q49667|B1308_F3_89 from Mycobacterium leprae (75 aa), FASTA scores: opt: 308, E(): 2.5e-15, (72.2% identity in 72 aa overlap); Q9R3X8|PRS1|USHX|PRS PRS1 PROTEIN (ANTI-SIGMA FACTOR) from Streptomyces coelicolor (137 aa), FASTA scores: opt: 184, E(): 3.7e-06, (36.8% identity in 106 aa overlap); O50231 PUTATIVE SIGMA-B REGULATOR from Bacillus licheniformis (160 aa), FASTA scores: opt: 122, E(): 0.13, (23.9% identity in 92 aa overlap); and P17904|RSBW_BACSU ANTI-SIGMA B FACTOR (SIGMA-B NEGATIVE EFFECTOR RSBW) from Bacillus subtilis (160 aa), FASTA scores: opt: 108, E(): 1.3, (21.25% identity in 127 aa overlap). Equivalent to AAK47729 from Mycobacterium tuberculosis strain CDC1551 (145 aa) but longer 99 aa. INDUCTION BY HEAT SHOCK, SALT STRESS,OXIDATIVE STRESS, GLUCOSE LIMITATION AND OXYGEN LIMITATION. N-terminus shortened since first submission (previously 242 aa). |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3623476 | 3623913 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3315c|rsbW
MADSDLPTKGRQRGVRAVELNVAARLENLALLRTLVGAIGTFEDLDFDAVADLRLAVDEVCTRLIRSALPDATLRLVVDPRKDEVVVEASAACDTHDVVAPGSFSWHVLTALADDVQTFHDGRQPDVAGSVFGITLTARRAASSR
Bibliography
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