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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPROBABLE TRANSCRIPTIONAL REGULATORY PROTEIN (PROBABLY TETR-FAMILY)
CommentsMb3323, -, len: 221 aa. Equivalent to Rv3295, len: 221 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 221 aa overlap). Probable transcriptional regulator tetR-family, equivalent to Q9CCL4|ML0717 PUTATIVE TETR-FAMILY TRANSCRIPTIONAL REGULATOR from Mycobacterium leprae (223 aa), FASTA scores: opt: 1260, E(): 7.2e-75, (85.45% identity in 220 aa overlap). Also highly similar to other streptomyces regulators e.g. Q9RD77|SCF43.11 from Streptomyces coelicolor (205 aa), FASTA scores: opt: 442, E(): 9.8e-22,(38.6% identity in 202 aa overlap); Q9RKY8|SC6D7.09 from Streptomyces coelicolor (220 aa), FASTA scores: opt: 215,E(): 5.9e-07, (31.85% identity in 135 aa overlap); Q9L0U5|SCD35.06 from Streptomyces coelicolor (240 aa),FASTA scores: opt: 214, E(): 7.4e-07, (28.2% identity in 156 aa overlap); etc. SIMILAR TO THE TETR/ACRR FAMILY OF TRANSCRIPTIONAL REGULATORS. Contains potential helix-turn-helix motif at aa 33-54 (+4.42 SD).
Functional categoryRegulatory proteins
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36305913631256+
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3323|Mb3323
MATARRRLSPQDRRAELLALGAEVFGKRPYDEVRIDEIAERAGVSRALMYHYFPDKRAFFAAVVKDEADRLYAATNKAPAPGMTMFEEIRTGVLAYMAYHQQNPEAAWAAYVGLGRSDPVLLGIDDEAKNRQMEHIMSRIAEVVSGIDRDNTLDPEVERDLRVIIHGWLAFTFELCRQRIMDPSTDAERLADACAHALLDAISRLPQIPAELADAMATARM
      
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