Gene Mb3326c in Mycobacterium bovis AF2122/97
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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
Gene summary information
Gene namelpqC
Gene length915 bp
IdentifierMb3326c
Location 3636635 bp
Protein summary information
Molecular mass31368.3 Da
Isoelectric point5.701
Protein length304 amino acids
Orthologs
M. tuberculosis H37RvRv3298c
M. tuberculosis MTBC0mtbc0_003506
Cross-references
UniProtKB/TrEMBLQ7TWS7
SWISS-MODELA0A1R3Y5I1
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE ESTERASE LIPOPROTEIN LPQC
CommentsMb3326c, lpqC, len: 304 aa. Equivalent to Rv3298c,len: 304 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 304 aa overlap). Possible lpqC,esterase lipoprotein (EC 3.1.-.-), equivalent to Q9CCL5|LPQC|ML0715 PUTATIVE SECRETED HYDROLASE from Mycobacterium leprae (304 aa), FASTA scores: opt: 1543,E(): 1.3e-87, (71.6% identity in 303 aa overlap); and Q49658|B1308_F2_43 TUBULIN FAMILY PROTEIN from Mycobacterium leprae (302 aa), FASTA scores: opt: 1541,E(): 1.7e-87, (72.0% identity in 300 aa overlap). Also similar to Q9I5Z3|PA0543 HYPOTHETICAL PROTEIN from Pseudomonas aeruginosa (322 aa), FASTA scores: opt: 439,E(): 8.9e-20, (32.3% identity in 319 aa overlap); Q9F2K9|SCH63.19c PUTATIVE SECRETED PROTEIN from Streptomyces coelicolor (348 aa), FASTA scores: opt: 394,E(): 5.5e-17, (30.25% identity in 334 aa overlap); etc. And similar to O86367|LPQP|Rv0671|MTCI376.03c from Mycobacterium tuberculosis strain H37Rv (280 aa), FASTA scores: opt: 519, E(): 9.8e-25, (39.25% identity in 275 aa overlap). Probably lipoprotein, esterase membrane-bound,with 18 aa signal sequence as it contains appropriately positioned (PS00013) Prokaryotic membrane lipoprotein lipid attachment site.
Functional category
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36366353637549-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3326c|lpqC
MPWARMLSLIVLMVCLAGCGGDQLLARHASSVATFQFGGLTRSYRLHVPPAEPSGLVISLHGGGGTGAGQEALTDFDAVADAADLLVVYPDGYDKSWADGRGASPADRRHLDDVGFLVALAAKLVHDFDIAPGHVFATGMSNGGFMSNRLACDRADIFAAVAPVAGTLGVGVTCNPSRPVSVLEAHGTADPLVPFNGGAVRGRGGLSHSISVASLVDRWRAVDGCQGDPSAAELPDVGDGTMVHLFDSSSCAAGTEVISYQIDNGGHTWPGGRQYLPKAVIGATTRAFDGSQVIAQFFATHGRD
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