Gene Mb3333c
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | possible n-acyl-l-amino acid amidohydrolase amia1 (n-acyl-l-amino acid aminohydrolase) |
| Comments | Mb3333c, amiA1, len: 389 aa. Equivalent to Rv3305c,len: 389 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 389 aa overlap). Possible amiA1,N-acyl-L-amino acid amidohydrolase (or peptidase) (EC 3.5.1.-), similar to many proteins e.g. Q9AK43|2SCK8.09 PUTATIVE PEPTIDASE from Streptomyces coelicolor (410 aa),FASTA scores: opt: 1015, E(): 3.9e-54, (50.8% identity in 374 aa overlap); Q9UZ30|PAB0873 AMINO ACID AMIDOHYDROLASE from Pyrococcus abyssi (383 aa), FASTA scores: opt: 823,E(): 1.6e-42, (38.2% identity in 369 aa overlap); O58453|PH0722 LONG HYPOTHETICAL AMINO ACID AMIDOHYDROLASE from Pyrococcus horikoshii (388 aa), FASTA scores: opt: 815, E(): 4.8e-42, (38.75% identity in 369 aa overlap); O34980|YTNL_BACSU HYPOTHETICAL 45.2 KDA PROTEIN from B. subtilis (416 aa), FASTA scores: opt: 805, E(): 2.1e-41,(37.85% identity in 367 aa overlap); Q9KCF8|BH1613 N-ACYL-L-AMINO ACID AMIDOHYDROLASE from Bacillus halodurans (404 aa), FASTA scores: opt: 795, E(): 8.1e-41,(37.7% identity in 382 aa overlap); BAB50445|MLR3583 HYPOTHETICAL HIPPURATE HYDROLASE from Rhizobium loti (Mesorhizobium loti) (387 aa), FASTA scores: opt: 761,E(): 8.9e-39, (37.65% identity in 385 aa overlap); Q9RXH4|DR0339 PUTATIVE N-ACYL-L-AMINO ACID AMIDOHYDROLASE from Deinococcus radiodurans (392 aa), FASTA scores: opt: 745, E(): 8.4e-38, (36.15% identity in 379 aa overlap); etc. Contains PS00639 Eukaryotic thiol (cysteine) proteases histidine active site. Note that previously known as amiA. |
| Functional category | |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3646164 | 3647333 | - |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3333c|amiA1
MSLADAAESWLAAHHDDLVGWRRHIHRYPELGRQEYATTQFVAERLADAGLNPKVLPGGTGLTCDFGPQHQPRIALRADMDALPMAERTGAPYASTMPNVAHACGHDAHTAILLGAALALASVPELPVGVRLIFQAAEELMPGGAIDAIAAGALAGVSRIFALHCDPRLEVGKVAVRQGPITSAADSIEITLYSPGGHTSRPHLTADLVYGLGTLVTGLPGVLSRRIDPRNSTVLVWGAVNAGMAANAIPQTGVLSGTVRTASRQTWVDLEELVRQAISALLLPLAIEHTLQYRRGVPPVVNEEISTRILAHAIEAIGPGVLADTRQSGGGEDFSWYLEEVPGAMARLGVWSGDGLQLDLHQPTFDIDERALAIGLRVMVNIIEQAAAH
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