Gene Mb3345
in Mycobacterium bovis AF2122/97
General annotation
| Type | CDS |
| Function | Unknown |
| Product | PROBABLE SUCCINATE DEHYDROGENASE (CYTOCHROME B-556 SUBUNIT) SDHC (SUCCINIC DEHYDROGENASE) (FUMARATE REDUCTASE) (FUMARATE DEHYDROGENASE) (FUMARIC HYDROGENASE) |
| Comments | Mb3345, sdhC, len: 112 aa. Equivalent to Rv3316,len: 112 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 112 aa overlap). Probable sdhC,cytochrome B-556 of succinate dehydrogenase SdhC subunit (EC 1.3.99.1), transmembrane protein, equivalent (but shorter 35 aa) to Q9CCM0|SDHC|ML0699 PUTATIVE SUCCINATE DEHYDROGENASE CYTOCHROME B-556 SUBUNIT from Mycobacterium leprae (153 aa), FASTA scores: opt: 692, E(): 1.2e-39,(88.4% identity in 112 aa overlap). Also similar to others e.g. Q9KZ88|SC5G8.26c from Streptomyces coelicolor (126 aa), FASTA scores: opt: 484, E(): 8.3e-26, (65.65% identity in 99 aa overlap); Q9RVR8|DR0954 from Deinococcus radiodurans (118 aa), FASTA scores: opt: 195, E(): 1.7e-06, (36.8% identity in 87 aa overlap); Q9HQ63|DHSD_HALN1|SDHD|SDHC|VNG1310G from Halobacterium sp. strain NRC-1 (130 aa), FASTA scores: opt: 192, E(): 2.9e-06, (37.85% identity in 74 aa overlap); P72109|DHSD_NATPH|SDHD|SDHC from Natronomonas pharaonis (Natronobacterium pharaonis) (130 aa), FASTA scores: opt: 183, E(): 1.1e-05, (35.15% identity in 74 aa overlap); etc. PART OF AN ENZYME COMPLEX CONTAINING FOUR SUBUNITS: A FLAVOPROTEIN, AN IRON-SULFUR, CYTOCHROME B-556, AND AN HYDROPHOBIC ANCHOR PROTEIN. BELONGS TO THE CYTOCHROME B560 FAMILY. |
| Functional category | Intermediary metabolism and respiration |
| Mutant | Check for mutants available at TARGET website |
Coordinates
| Type | Start | End | Orientation |
|---|---|---|---|
| CDS | 3658627 | 3658965 | + |
Genomic sequence
Feature type
Upstream flanking region (bp)
Downstream flanking region (bp)
Update
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3345|sdhC
MWSWVCHRISGATIFFFLFVHVLDAAMLRVSPQTYNAVLATYKTPIVGLMEYGLVAAVLFHALNGIRVILIDFWSEGPRYQRLMLWIIGSVFLLLMVPAGVVVGIHMWEHFR
Bibliography
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