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virulence, detoxification, adaptation
information pathways
cell wall and cell processes
stable RNAs
insertion seqs and phages
PE/PPE
intermediary metabolism and respiration
unknown
regulatory proteins
conserved hypotheticals
lipid metabolism
pseudogenes
General annotation
TypeCDS
FunctionUnknown
ProductPOSSIBLE METHYLTRANSFERASE
CommentsMb3351c, -, len: 204 aa. Equivalent to Rv3322c,len: 204 aa, from Mycobacterium tuberculosis strain H37Rv,(100.0% identity in 204 aa overlap). Conserved hypothetical protein, showing weak similarity to proteins including several methyltransferases (EC 2.1.1.-) e.g. Q9X9V1|ORF8 PUTATIVE METHYLTRANSFERASE from Streptomyces coelicolor (208 aa), FASTA scores: opt: 193, E(): 1e-05,(36.35% identity in 132 aa overlap); and Q9XA90|SCF43A.25c PUTATIVE METHYLTRANSFERASE from Streptomyces coelicolor (215 aa), FASTA scores: opt: 161, E(): 0.0014, (32.05% identity in 131 aa overlap); P74712|SLR1183 HYPOTHETICAL 21.3 KDA PROTEIN from Synechocystis sp. strain PCC 6803 (194 aa), FASTA scores: opt: 155, E(): 0.0032, (27.35% identity in 150 aa overlap); Q9ABW8|CC0102 RRNA METHYLTRANSFERASE RSMB from Caulobacter crescentus (429 aa), FASTA scores: opt: 148, E(): 0.018, (31.5% identity in 162 aa overlap); etc. Also highly similar to O05796|Rv3120|MTCY164.30 HYPOTHETICAL 21.8 KDA PROTEIN from Mycobacterium tuberculosis (200 aa), FASTA scores: opt: 691, E(): 1.2e-38, (56.5% identity in 200 aa overlap); and shows weak similarity to O69667|Rv3699|MTV025.047 PUTATIVE METHYLTRANSFERASE from Mycobacterium tuberculosis (233 aa), FASTA scores: opt: 155, E(): 0.0037, (29.15% identity in 168 aa overlap).
Functional categoryIntermediary metabolism and respiration
Mutant
Check for mutants available at TARGET website
Coordinates
TypeStartEndOrientation
CDS36629603663574-
Genomic sequence
Feature type Upstream flanking region (bp) Downstream flanking region (bp) Update
       
Protein sequence
>Mycobacterium bovis AF2122-97|Mb3351c|Mb3351c
MSVQTDPALREHPNRVDWNARYERAGSAHAPFAPVPWLADVLRAGVPDGPVLELASGRSGTALALAAHGRQVTAIDVSDVALLQLDSEAVRRGVADRLNLVQADLGCWEPGETRFALVLSRLFWDAAIFHRACEAVMPGGVLAWESLALSGAEAGTASAKRRVKPGEPACLLPADFTVVHEGQGNCDSAPSRIMIARRSPLPGA
      
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